1887

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Volume 66, Issue 8

Novel adenoviruses detected in British mustelids, including a unique in the tissues of pine martens () Open Access

Abstract

Several adenoviruses are known to cause severe disease in veterinary species. Recent evidence suggests that canine adenovirus type 1 (CAV-1) persists in the tissues of healthy red foxes (), which may be a source of infection for susceptible species. It was hypothesized that mustelids native to the UK, including pine martens () and Eurasian otters (), may also be persistently infected with adenoviruses. Based on high-throughput sequencing and additional Sanger sequencing, a novel , tentatively named marten adenovirus type 1 (MAdV-1), was detected in pine marten tissues. The detection of an in mammalian tissue has not been reported previously. Two mastadenoviruses, tentatively designated marten adenovirus type 2 (MAdV-2) and lutrine adenovirus type 1 (LAdV-1), were also detected in tissues of pine martens and Eurasian otters, respectively. Apparently healthy free-ranging animals may be infected with uncharacterized adenoviruses with possible implications for translocation of wildlife.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): adenovirus , cross-species transmission , high-throughput sequencing , otter and pine marten
© 2017 The Authors
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2017-08-01
2024-04-19
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References

  1. Lion T. Adenovirus infections in immunocompetent and immunocompromised patients. Clin Microbiol Rev 2014; 27:441–462 [View Article][PubMed]
     [Google Scholar]
  2. Ronchi A, Doern C, Brock E, Pugni L, Sánchez PJ. Neonatal adenoviral infection: a seventeen year experience and review of the literature. J Pediatr 2014; 164:529–535 [View Article][PubMed]
     [Google Scholar]
  3. Decaro N, Campolo M, Elia G, Buonavoglia D, Colaianni ML et al. Infectious canine hepatitis: an "old" disease reemerging in Italy. Res Vet Sci 2007; 83:269–273 [View Article][PubMed]
     [Google Scholar]
  4. Walker D, Abbondati E, Cox AL, Mitchell GB, Pizzi R et al. Infectious canine hepatitis in red foxes (Vulpes vulpes) in wildlife rescue centres in the UK. Vet Rec 2016; 178:421 [View Article][PubMed]
     [Google Scholar]
  5. Buonavoglia C, Martella V. Canine respiratory viruses. Vet Res 2007; 38:355–373 [View Article][PubMed]
     [Google Scholar]
  6. Lehmkuhl HD, Cutlip RC, Debey BM. Isolation of a bovine adenovirus serotype 10 from a calf in the United States. J Vet Diagn Invest 1999; 11:485–490 [View Article][PubMed]
     [Google Scholar]
  7. Vaatstra BL, Tisdall DJ, Blackwood M, Fairley RA. Clinicopathological features of 11 suspected outbreaks of bovine adenovirus infection and development of a real-time quantitative PCR to detect bovine adenovirus type 10. N Z Vet J 2016; 64:308–313 [View Article][PubMed]
     [Google Scholar]
  8. Fitzgerald SD, Reed WM. A review of marble spleen disease of ring-necked pheasants. J Wildl Dis 1989; 25:455–461 [View Article][PubMed]
     [Google Scholar]
  9. Hess M. Detection and differentiation of avian adenoviruses: a review. Avian Pathol 2000; 29:195–206 [View Article][PubMed]
     [Google Scholar]
  10. Niu YJ, Sun W, Zhang GH, Qu YJ, Wang PF et al. Hydropericardium syndrome outbreak caused by fowl adenovirus serotype 4 in China in 2015. J Gen Virol 2016; 97:2684–2690 [View Article][PubMed]
     [Google Scholar]
  11. Garnett CT, Erdman D, Xu W, Gooding LR. Prevalence and quantitation of species C adenovirus DNA in human mucosal lymphocytes. J Virol 2002; 76:10608–10616 [View Article][PubMed]
     [Google Scholar]
  12. Roy S, Vandenberghe LH, Kryazhimskiy S, Grant R, Calcedo R et al. Isolation and characterization of adenoviruses persistently shed from the gastrointestinal tract of non-human primates. PLoS Pathog 2009; 5:e1000503 [View Article][PubMed]
     [Google Scholar]
  13. Lee SY, Kim JH, Seo TK, No JS, Kim H et al. Genetic and molecular epidemiological characterization of a novel adenovirus in Antarctic penguins collected between 2008 and 2013. PLoS One 2016; 11:e0157032 [View Article][PubMed]
     [Google Scholar]
  14. Walker D, Fee SA, Hartley G, Learmount J, O'Hagan MJ et al. Serological and molecular epidemiology of canine adenovirus type 1 in red foxes (Vulpes vulpes) in the United Kingdom. Sci Rep 2016; 6:36051 [View Article][PubMed]
     [Google Scholar]
  15. Parry HB. Viral hepatitis of dogs (Rubarth's disease). I. Clinical and pathological observations on a spontaneous epidemic. Vet Rec 1950; 62:359–365 [View Article][PubMed]
     [Google Scholar]
  16. Everest DJ, Shuttleworth CM, Stidworthy MF, Grierson SS, Duff JP et al. Adenovirus: an emerging factor in red squirrel Sciurus vulgaris conservation. Mamm Rev 2014; 44:225–233 [View Article]
     [Google Scholar]
  17. Balboni A, Verin R, Morandi F, Poli A, Prosperi S et al. Molecular epidemiology of canine adenovirus type 1 and type 2 in free-ranging red foxes (Vulpes vulpes) in Italy. Vet Microbiol 2013; 162:551–557 [View Article][PubMed]
     [Google Scholar]
  18. Veterinary Record Pine marten project gets underway. Vet Rec 2015; 177:384 [View Article][PubMed]
     [Google Scholar]
  19. Decaro N, Buonavoglia C, Eatwell K, Erdélyi K, Duff JP et al. Adenovirus infections. In Gavier-Widén D, Duff JP, Meredith A. (editors) Infectious Diseases of Wild Mammals and Birds in Europe Oxford, UK: Wiley-Blackwell; 2012 pp. 210–218 [CrossRef]
     [Google Scholar]
  20. Park NY, Lee MC, Kurkure NV, Cho HS. Canine adenovirus type 1 infection of a Eurasian river otter (Lutra lutra). Vet Pathol 2007; 44:536–539 [View Article][PubMed]
     [Google Scholar]
  21. Kozak RA, Ackford JG, Slaine P, Li A, Carman S et al. Characterization of a novel adenovirus isolated from a skunk. Virology 2015; 485:16–24 [View Article][PubMed]
     [Google Scholar]
  22. Philippa J, Fournier-Chambrillon C, Fournier P, Schaftenaar W, van de Bildt M et al. Serologic survey for selected viral pathogens in free-ranging endangered European mink (Mustela lutreola) and other mustelids from south-western France. J Wildl Dis 2008; 44:791–801 [View Article][PubMed]
     [Google Scholar]
  23. Byrnes AP. Antibodies against adenoviruses. In Curiel DT. (editor) Adenoviral Vectors for Gene Therapy London, UK: Academic Press; 2016 pp. 367–390 [CrossRef]
     [Google Scholar]
  24. Willcox N, Mautner V. Antigenic determinants of adenovirus capsids I. Measurement of antibody cross-reactivity. J Immunol 1976; 116:19–24[PubMed]
     [Google Scholar]
  25. Wellehan JF, Johnson AJ, Harrach B, Benkö M, Pessier AP et al. Detection and analysis of six lizard adenoviruses by consensus primer PCR provides further evidence of a reptilian origin for the atadenoviruses. J Virol 2004; 78:13366–13369 [View Article][PubMed]
     [Google Scholar]
  26. Johnson M, Zaretskaya I, Raytselis Y, Merezhuk Y, Mcginnis S et al. NCBI BLAST: a better web interface. Nucleic Acids Res 2008; 36:W5–W9 [View Article][PubMed]
     [Google Scholar]
  27. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 2013; 30:2725–2729 [View Article][PubMed]
     [Google Scholar]
  28. Simmonds P. SSE: a nucleotide and amino acid sequence analysis platform. BMC Res Notes 2012; 5:50 [View Article][PubMed]
     [Google Scholar]
  29. Wevers D, Leendertz FH, Scuda N, Boesch C, Robbins MM et al. A novel adenovirus of Western lowland gorillas (Gorilla gorilla gorilla). Virol J 2010; 7:303 [View Article][PubMed]
     [Google Scholar]
  30. Chen EC, Yagi S, Kelly KR, Mendoza SP, Tarara RP et al. Cross-species transmission of a novel adenovirus associated with a fulminant pneumonia outbreak in a new world monkey colony. PLoS Pathog 2011; 7:e1002155 [View Article][PubMed]
     [Google Scholar]
  31. Phan TG, Kapusinszky B, Wang C, Rose RK, Lipton HL et al. The fecal viral flora of wild rodents. PLoS Pathog 2011; 7:e1002218 [View Article][PubMed]
     [Google Scholar]
  32. Zheng XY, Qiu M, Ke XM, Guan WJ, Li JM et al. Detection of novel adenoviruses in fecal specimens from rodents and shrews in southern China. Virus Genes 2016; 52:417–421 [View Article][PubMed]
     [Google Scholar]
  33. Davison AJ, Benko M, Harrach B. Genetic content and evolution of adenoviruses. J Gen Virol 2003; 84:2895–2908 [View Article][PubMed]
     [Google Scholar]
  34. Madarame H, Ogihara K, Ochiai H, Omatsu T, Mizutani T. Detection of skunk adenovirus 1 (SkAdV-1) in an African pigmy hedgehog (Atelerix albiventris). Vet Rec Case Rep 2016; 4:e000321 [View Article]
     [Google Scholar]
  35. Kock RA, Woodford MH, Rossiter PB. Disease risks associated with the translocation of wildlife. Rev Sci Tech 2010; 29:329–350 [View Article][PubMed]
     [Google Scholar]
  36. IUCN Species Survival Commission Guidelines for Reintroductions and Other Conservation Translocations, Version 1.0 Gland, Switzerland: International Union for Conservation of Nature; 2013
     [Google Scholar]
  37. Larkin MA, Blackshields G, Brown NP, Chenna R, Mcgettigan PA et al. CLUSTAL W and CLUSTAL X version 2.0. Bioinformatics 2007; 23:2947–2948 [View Article][PubMed]
     [Google Scholar]
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Novel adenoviruses detected in British mustelids, including a unique Aviadenovirus in the tissues of pine martens (Martes martes)
J. Med. Microbiol. 66, 1177 (2017); https://doi.org/10.1099/jmm.0.000546
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