Effects of Oral Treatment with Acyclovir and Bromovinyldeoxyuridine on the Establishment and Maintenance of Latent Herpes Simplex Virus Infection in Mice

References

1. Blyth W. A., Harbour D. A., Hill T. J. 1980; Effect of acyclovir on recurrence of herpes simplex skin lesions in mice. Journal of General Virology 48:417–419
   [Google Scholar]
2. Boulter E. A., Thornton B., Bauer D. J., Bye A. 1980; Successful treatment of experimental B virus (herpesvirus simiae) infection with acyclovir. British Medical Journal 280:681–683
   [Google Scholar]
3. Darby G., Larder B. A., Bastow K. F., Field H. J. 1980; Sensitivity of viruses to phosphorylated 9(2-hydroxyethoxymethyl)guanine revealed in TK-transformed cells. Journal of General Virology 48:451–454
   [Google Scholar]
4. De Clercq E., Descamps J., De Somer P., Barr P. J., Jones A. S., Walker R. T. 1979a; (E)-5-(2-bromovinyl)-2′-deoxyuridine; a potent and selective anti-herpes agent. Proceedings of the National Academy of Sciences of the United States of America 76:2947–2951
   [Google Scholar]
5. De Clercq E., Descamps J., De Somer P., Barr P. J., Jones A. S., Walker R. T. 1979b; PharmokineticS of E-5-(2-bromovinyl)-2′-deoxyuridine in mice. Antimicrobial Agents and Chemotherapy 16:234–236
   [Google Scholar]
6. Elion G. B., Furman P. A., Fyfe J. A., De Miranda P., Beauchamp L., Schaeffer H. J. 1977; Selective action of an antiherpetic agent, 9(2-hydroxyethoxymethyl)guanine. Proceedings of the National Academy of Sciences of the United States of America 74:5716–5720
   [Google Scholar]
7. Field H. J., Darby G. K. 1980; Strategies of drug resistance in herpes simplex. Nature, London 286:842
   [Google Scholar]
8. Field H. J., Bell S. E., Elion G. B., Nash A. A., Wildy P. 1979; Effect of acycloguanosine treatment on acute and latent herpes simplex infections in mice. Antimicrobial Agents and Chemotherapy 15:554–561
   [Google Scholar]
9. Field H. J., Darby G., Wildy P. 1980; Isolation and characterization of acyclovir-resistant mutants of herpes simplex virus. Journal of General Virology 49:115–124
   [Google Scholar]
10. Fong B. S., Scriba M. 1980; Use of [¹²⁵I deoxycytidine to detect herpes simplex virus specific thymidine kinase in tissues of latently infected guinea pigs. Journal of Virology 34:644–649
    [Google Scholar]
11. Furman P. A., McGuirt P. V., Keller P. M., Fyfe J. A., Elion G. B. 1980; Inhibition by acyclovir of cell growth and DNA synthesis of cells biochemically transformed with herpes virus genetic information. Virology 102:420–430
    [Google Scholar]
12. Fyfe J. A., Keller P. M., Furman P. A., Miller R. L., Elion G. B. 1978; Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine. Journal of Biological Chemistry 253:8721–8727
    [Google Scholar]
13. Hill T. J., Field H. J., Blyth W. A. 1975; Acute and recurrent infection with herpes simplex in the mouse: a model for studying latency and recurrent disease. Journal of General Virology 28:341–353
    [Google Scholar]
14. Kaufman H. E., Varnell E. D., Centifanto Y. M., Rheinstrom S. D. 1978; Effect of 9-(2-hydroxyethoxymethyl-guanine on herpesvirus-induced keratitis and iritis in rabbits. Antimicrobial Agents and Chemotherapy 14:842–845
    [Google Scholar]
15. Klein R. J., Friedman-Kien A. E., Yellin P. B. 1978; Orofacial herpes simplex virus infection in hairless mice: latent virus in trigeminal ganglia after topical antiviral treatment. Infection and Immunity 20:130–135
    [Google Scholar]
16. Klein R. J., Friedman-Kien A. E., De Stefano E. 1979; Latent herpes simplex virus infection in sensory ganglia of hairless mice prevented by acycloguanosine. Antimicrobial Agents and Chemotherapy 15:723–729
    [Google Scholar]
17. Maudgal P. C., De Clercq E., Descamps J., Missotten L., DE Somer P., Busson R., Vanderhaeghe H., Verhelst G., Walker R. T., Jones A. S. 1980; (E)-5-(2-bromovinyl)-2′-deoxyuridine in the treatment of experimental herpes simplex keratitis. Antimicrobial Agents and Chemotherapy 17:8–12
    [Google Scholar]
18. Nash A. A., Field H. J., Quartey-Papafio R. 1980; Cell-mediated immunity in herpes simplex virus-infected mice: induction, characterization and antiviral effects of delayed type hypersensitivity. Journal of General Virology 48:351–357
    [Google Scholar]
19. Nishiyama Y., Rapp F. 1979; Anticellular effects of 9-(2-hydroxyethoxymethyl)guanine against herpes simplex virus transformed cells. Journal of General Virology 45:227–230
    [Google Scholar]
20. Park N. H., Pavan-Langston D., Mclean S. L. 1979; Acyclovir in oral and ganglionic herpes simplex virus infections. Journal of Infectious Diseases 140:802–806
    [Google Scholar]
21. Pavan-Langston D., Park N. H., Lass J. 1979; Herpetic ganglionic latency. Acyclovir and vidarabine therapy. Archives of Ophthalmology 97:1508–1510
    [Google Scholar]
22. Schaeffer H. J., Beauchamp L., De Miranda P., Elion G. B., Bauer D. J., Collins P. 1977; 9-(2-hydroxyethoxymethyl)guanine activity against viruses of the herpes group. Nature, London 272:583–585
    [Google Scholar]
23. Yamamoto H., Walz M. A., Notkins A. L. 1977; Viral-specific thymidine kinase in sensory ganglia of mice infected with herpes simplex virus. Virology 76:866–869
    [Google Scholar]