Clinical StudiesTranscatheter Thrombolytic Therapy for Acute Mesenteric and Portal Vein Thrombosis
Section snippets
MATERIALS AND METHODS
In this retrospective study, billing records were searched to identify patients with Current Procedural Terminology codes corresponding to PV access, thrombolytic drug infusion, selective catheterization, and/or visceral angiography. The study was approved by the institutional review board, which determined the study was exempted from obtaining patient consent.
Radiographic Evidence of Success
The procedure resulted in lysis of thrombus in the majority of patients (Table 1, Table 2, Table 3). Overall, 15 of 20 patients (75%) experienced some degree of lysis. Three patients experienced complete lysis and 12 patients experienced partial lysis. Of patients with class 6 disease, three had no lysis, nine had partial lysis, and one had complete lysis (Table 1).
There were four patients who had not received transplants who did not exhibit any lysis. Two of these four patients developed major
DISCUSSION
Mesenteric vein thrombosis can lead to bowel infarction and death, with reported mortality rates of 13%–50% (8). A study on mesenteric vein thrombosis with a variety of treatments reported that eight of 23 patients with acute thrombus required bowel resection and there was a 30day mortality rate of 30% (14). As part of a retrospective study, Rhee et al (15) examined 53 patients with acute mesenteric vein thrombosis treated at their institution over a period of 21 years. Thirty patients required
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None of the authors have identified a conflict of interest.