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Hum. Reprod. Advance Access originally published online on May 5, 2006
Human Reproduction 2006 21(8):2114-2120; doi:10.1093/humrep/del110
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© The Author 2006. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. for Permissions, please email: journals.permissions@oxfordjournals.org The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org

Auricular electro-acupuncture as an additional perioperative analgesic method during oocyte aspiration in IVF treatment

Sabine M. Sator-Katzenschlager1,5, Monika M. Wölfler2, Sibylle A. Kozek-Langenecker1, Kathrin Sator2, Paul-G. Sator3, Borwen Li1, Georg Heinze4 and Michael O. Sator2

1 Department of Anesthesiology and Intensive Care Medicine (B) 2 Department of Gynecology and Obstetrics 3 Department of Special and Environmental Dermatology and 4 Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Vienna, Austria

5 To whom correspondence should be addressed at: Department of Anesthesiology and Intensive Care Medicine (B), University of Vienna, Waehringer Guertel 18–20, A-1090 Vienna, Austria. E-mail: sabine.sator-katzenschlager{at}meduniwien.ac.at

BACKGROUND: The aim of this study was to compare the pain-relieving effect and the subjective well-being between auricular electro-acupuncture (EA) analgesia, auricular acupuncture (A) and conventional analgesia with remifentanil (CO). METHODS: A total of 94 women undergoing IVF were randomized to auricular acupuncture with (EA, n = 32) or without (A, n = 32) continuous 1 Hz auricular stimulation (using a battery-powered miniaturized stimulator, P-Stim) or with adhesive tapes instead of needles and no electrical stimulation (control group, CO, n = 30) at the auricular acupuncture points 29, 55 and 57. All patients received patient-controlled analgesia (PCA) with remifentanil. Pain intensity and psychological well-being were assessed by means of visual analogue scales (VAS); tiredness, nausea and vomiting and analgesic drug consumption were documented. RESULTS: Pain relief and subjective well-being were significantly greater in group EA during and after the procedure as compared with groups A and CO (P < 0.001). The patients were significantly more tired in group CO than in groups A and EA (P < 0.001). Consumption of the opioid remifentanil was significantly lower in group EA, comparable nausea (P < 0.001). CONCLUSION: Auricular EA significantly reduces pain intensity and analgesic consumption of the opioid remifentanil during oocyte aspiration in IVF treatment.

Key words: analgesia/auricular electro-acupuncture/IVF/oocyte aspiration/pain relief/remifentanil


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