Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets123
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KEY WORDS
Obesity
hyperinsulinemia
hepatic de novo lipogenesis
triacylglycerols
triglycerides
hypertriglyceridemia
hyperlipidemia
cardiovascular disease
heart disease
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From the Department of Nutritional Sciences and Toxicology, University of California, Berkeley (J-MS and KA), and the Department of Medicine, University of California, San Francisco (J-MS, PL, and DD).
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Supported in part by the American Heart Association (no. 97-30-202N), the US Department of Agriculture, and the American Diabetes Association (Clinical Research Award). A National Institutes of Health grant (RR00083-37) from the Division of Research Resources supported the General Clinical Research Center at San Francisco General Hospital.
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Address reprint requests to J-M Schwarz, Department of Nutritional Sciences and Toxicology, 119 Morgan Hall, University of California Berkeley, Berkeley, CA 94720-3104. E-mail:[email protected].
Copyright © 2003 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.