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Integrative Modeling of Electrical Properties of Pacemaker Cardiac Cells

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, , Citation M Grigoriev and L Babich 2016 IOP Conf. Ser.: Mater. Sci. Eng. 132 012007 DOI 10.1088/1757-899X/132/1/012007

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mishatpu@mail.ru

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1 Engineer, National Research Tomsk Polytechnic University, Tomsk, Russia

2 Student, National Research Tomsk Polytechnic University, Tomsk, Russia

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1757-899X/132/1/012007

Abstract

This work represents modeling of electrical properties of pacemaker (sinus) cardiac cells. Special attention is paid to electrical potential arising from transmembrane current of Na+, K+ and Ca2+ ions. This potential is calculated using the NaCaX model. In this respect, molar concentration of ions in the intercellular space which is calculated on the basis of the GENTEX model is essential. Combined use of two different models allows referring this approach to integrative modeling.

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10.1088/1757-899X/132/1/012007