Cherenkov imaging in the potential roles of radiotherapy QA and delivery

Cherenkov emission has a direct proportionality to the deposited dose at the local level, and capture of these emitted light signals allows visualization of real time maps of dose in vivo. Mapping the Cherenkov signals through water tanks illustrates how 3D Cherenkov can be achieved, either as 2D plus time, or 3D in static imaging. Imaging Cherenkov from patients shows how signals can be acquired which map out radiation dose in real time. The signals are affected by several factors, each of which will take some calibration to resolve, yet intrinsically the signal is shown to be a linear reporter of dose delivered. Development of calibration methodologies is ongoing in both research and development work.