GENERAL

Dynamical Effect of Calcium Pump on Cytosolic Calcium Bursting Oscillations with IP3 Degradation

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2010 Chinese Physical Society and IOP Publishing Ltd
, , Citation Meng Pan and Lu Qi-Shao 2010 Chinese Phys. Lett. 27 010502 DOI 10.1088/0256-307X/27/1/010502

0256-307X/27/1/010502

Abstract

Taking account of the Ca2+-activated degradation of inositol trisphosphate (IP3), a one pool model of cytosolic calcium oscillation is considered to investigate the effect of the calcium pump on the Ca2+ bursting oscillation behavior. In order to give the oscillation domain, a two-parameter bifurcation analysis of the fast subsystem is performed in the parameter plane. Different types of bursting are presented with the variation of the pump parameter, and fast-slow dynamics is used to analyze the types and generation mechanisms of the bursting oscillations. The results are instructive for understanding the role of the calcium pump played in complex intracellular calcium activities.

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10.1088/0256-307X/27/1/010502