Quantitative reflection spectroscopy at the human ocular fundus

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Published 4 January 2002 Published under licence by IOP Publishing Ltd
, , Citation Martin Hammer and Dietrich Schweitzer 2002 Phys. Med. Biol. 47 179 DOI 10.1088/0031-9155/47/2/301

0031-9155/47/2/179

Abstract

A new model of the reflection of the human ocular fundus on the basis of the adding–doubling method, an approximate solution of the radiative transport equation, is described. This model enables the calculation of the concentrations of xanthophyll in the retina, of melanin in the retinal pigment epithelium and the choroid, and of haemoglobin in the choroid from fundus reflection spectra. The concentration values found in 12 healthy subjects are in excellent agreement with published data. In individual cases of pathologic fundus alterations, possible benefits to the ophthalmologic diagnostics are demonstrated.

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