Role of Ureaplasma urealyticum and Chlamydia trachomatis in lung disease in low birth weight infants
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Cited by (38)
Ureaplasma and BPD
2013, Seminars in PerinatologyCitation Excerpt :However, the contribution of Ureaplasma or chorioamnionitis to BPD is less clear. Several single center studies reported the association of Ureaplasma in the respiratory secretions of newborns with the development of BPD.54–58 Some studies used the BPD definition of oxygen supplementation at 28 days, while others used the more current definition of BPD as the need for oxygen supplementation at 36 weeks post-menstrual age.
Prenatal and Postnatal Microbial Colonization and Respiratory Outcome in Preterm Infants
2012, The Newborn Lung: Neonatology Questions and Controversies Expert ConsultPrenatal and Postnatal Microbial Colonization and Respiratory Outcome in Preterm Infants
2012, The Newborn LungMycoplasmal infections
2010, Infectious Diseases of the Fetus and Newborn: Expert Consult - Online and PrintThe bacterial load of Ureaplasma parvum in amniotic fluid is correlated with an increased intrauterine inflammatory response
2010, Diagnostic Microbiology and Infectious DiseaseCitation Excerpt :However, there are still controversial results from different studies investigating the role of Ureaplasma spp. and clinical outcomes of preterm infants. It seems that infection with these organisms triggers a vigorous proinflammatory response in the lungs facilitating development of BPD (Abele-Horn et al., 1998; Cassell et al., 1988; Colaizy et al., 2007; Garland and Bowman 1996), but this association remains controversial (Da Silva et al., 1997; Heggie et al., 2001; Ollikainen et al., 2001). In this context, the finding that a high percentage of sexually active women has vaginal colonization with Ureaplasma spp. (40–80%) (Waites et al., 2005) but normal term deliveries and that, correspondingly, many preterm infants are exposed to intrauterine Ureaplasma infection but have normal pulmonary and neurologic outcomes highlights the relevance of additional factors in the pathogenicity of these clinical entities, possibly including different Ureaplasma serovars and different bacterial loads.
Mycoplasmal Infections
2010, Infectious Diseases of the Fetus and Newborn Infant