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Iron Deficiency and the Measurement of Iron Status

Published online by Cambridge University Press:  14 December 2007

James D. Cook
Affiliation:
Division of Hematology, Department of Internal Medicine, Kansas University Medical Center, Kansas City, Kansas 66160-7402, USA
Roy D. Baynes
Affiliation:
Division of Hematology, Department of Internal Medicine, Kansas University Medical Center, Kansas City, Kansas 66160-7402, USA
Barry S. Skikne
Affiliation:
Division of Hematology, Department of Internal Medicine, Kansas University Medical Center, Kansas City, Kansas 66160-7402, USA
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Abstract

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Type
Research Article
Copyright
Copyright © The Nutrition Society 1992

References

REFERENCES

Bassett, M. L., Halliday, J. W., Bryant, S., Dent, O. & Powell, L. W. (1988). Screening for hemochromatosis. Annals of the New York Academy of Sciences 526, 274289.CrossRefGoogle ScholarPubMed
Baynes, R. D., Flax, H., Bothwell, T. H., Bezwoda, W. R., Atkinson, P. & Mendelow, B. (1986). Red blood cell distribution width in the anemia secondary to tuberculosis. American Journal of Clinical Pathology 85, 226229.CrossRefGoogle ScholarPubMed
Bessman, J. D. & Feinstein, D. I. (1979). Quantitative anisocytosis as a discriminant between iron deficiency and thalassemia minor. Blood 53, 288293.CrossRefGoogle ScholarPubMed
Bezwoda, W. R., Bothwell, T. H., Derman, D. P., MacPhail, A. P., Torrance, J. D. & Charlton, R. W. (1981). Effect of diet on the rate of iron accumulation in idiopathic haemochromatosis. South African Medical Journal 59, 219222.Google ScholarPubMed
Bothwell, T. H., Charlton, R. W., Cook, J. D. & Finch, C. A. (1979). Iron Metabolism in Man, 576 pp. Oxford: Blackwell Scientific Publications.Google Scholar
Bothwell, T. H., Charlton, R. W. & Motulsky, A. (1989). Hemochromatosis. In The Metabolic Basis of Inherited Disease, p. 1433 [Scriver, C. R.Beaudet, A. L.Sly, W. S. et al. , editors]. New York: McGraw-Hill.Google Scholar
Carriaga, M. T., Skikne, B. S., Finley, B., Cutler, B. & Cook, J. D. (1991). Serum transferrin receptor for the detection of iron deficiency in pregnancy. American Journal of Clinical Nutrition 54, 10771081.CrossRefGoogle ScholarPubMed
Cash, J. M. & Sears, D. A. (1989). The anemia of chronic disease: spectrum of associated diseases in a series of unselected hospitalized patients. American Journal of Medicine 87, 638644.CrossRefGoogle Scholar
Charlton, R. W., Derman, D., Skikne, B., Torrance, J. D., Lynch, S. R., Sayers, M. H., Zwi, S., Goldman, H. I., Van As, A., Margo, G., Schneider, J. T. & Bothwell, T. H. (1977). Anaemia, iron deficiency and exercise: extended studies in human subjects. Clinical Science and Molecular Medicine 53, 537541.Google ScholarPubMed
Cook, J. D. (1982). Clinical evaluation of iron deficiency. Seminars in Hematology 19, 618.Google ScholarPubMed
Cook, J. D. & Lynch, S. R. (1986). Review. The liabilities of iron deficiency. Blood 68, 803809.CrossRefGoogle ScholarPubMed
Cook, J. D. & Skikne, B. S. (1989). Iron deficiency: definition and diagnosis. Journal of Internal Medicine 226, 349355.CrossRefGoogle ScholarPubMed
Cook, J. D., Skikne, B. S., Lynch, S. R. & Reusser, M. E. (1986). Estimates of iron sufficiency in the US population. Blood 68, 726731.CrossRefGoogle ScholarPubMed
Dallman, P. R. (1982). Manifestations of iron deficiency. Seminars in Hematology 19, 1930.Google ScholarPubMed
Dallman, P. R. (1989). Iron deficiency: does it matter? Journal of Internal Medicine 226, 367372.CrossRefGoogle ScholarPubMed
DeMaeyer, E. & Adiels-Tegman, M. (1985). The prevalence of anaemia in the world. World Health Statistics Quarterly 38, 302316.Google ScholarPubMed
Edwards, C. Q., Griffen, L. M., Goldgar, D., Drummond, C., Skolnick, M. H. & Kushner, J. P. (1988). Prevalence of hemochromatosis among 11,065 presumably healthy blood donors. New England Journal of Medicine 318, 13551362.CrossRefGoogle ScholarPubMed
Finch, C. A., Bellotti, V., Stray, S., Lipschitz, D. A., Cook, J. D., Pippard, M. J. & Huebers, H. A. (1986). Plasma ferritin determination as a diagnostic tool. Western Journal of Medicine 145, 657663.Google ScholarPubMed
Flowers, C. H., Skikne, B. S., Covell, A. M. & Cook, J. D. (1989). The clinical measurement of serum transferrin receptor. Journal of Laboratory and Clinical Medicine 114, 368377.Google ScholarPubMed
Flynn, M. M., Reppun, T. S. & Bhagavan, N. V. (1986). Limitations of red blood cell distribution width (RDW) in evaluation of microcytosis. American Journal of Clinical Pathology 85, 445449.CrossRefGoogle ScholarPubMed
Garby, L., Irnell, L. & Werner, I. (1969). Iron deficiency in women of fertile age in a Swedish community. III. Estimation of prevalence based on response to iron supplementation. Acta Medica Scandinavica 185, 113117.CrossRefGoogle Scholar
Gardner, G. R., Edgerton, B. R., Senewiratne, B., Barnard, R. J. & Ohira, Y. (1977). Physical work capacity and metabolic stress in subjects with iron deficiency anemia. American Journal of Clinical Nutrition 30, 910917.CrossRefGoogle ScholarPubMed
Garn, S. M., Ridella, S. A., Tetzold, A. S. & Falkner, F. (1981). Maternal haematological levels and pregnancy outcomes. Seminars in Perinatology 5, 155162.Google ScholarPubMed
Huebers, H. A., Beguin, Y., Pootrakul, P., Einspahr, D. & Finch, C. A. (1990). Intact transferrin receptors in human plasma and their relation to erythropoiesis. Blood 75, 102107.CrossRefGoogle ScholarPubMed
Huebers, H. A. & Finch, C. A. (1987). The physiology of transferrin and transferrin receptors. Physiological Reviews 67, 520582.CrossRefGoogle ScholarPubMed
International Committee for Standardization in Haematology (1984). Preparation, characterization and storage of human ferritin for use as a standard for the assay of serum ferritin. Clinical and Laboratory Haematology 6, 177191.Google Scholar
Irie, S. & Tavassoli, M. (1987). Transferrin-mediated cellular iron uptake. American Journal of the Medical Sciences 293, 103111.CrossRefGoogle ScholarPubMed
Jacobs, A. (1985). Ferritin: an interim review. Current Topics in Hematology 5, 2562.Google ScholarPubMed
Jensen, B. M., Sandø, S. H., Grandjean, P., Wiggers, P. & Dalhøj, J. (1990). Screening with zinc protoporphyrin for iron deficiency in non-anemic female blood donors. Clinical Chemistry 36, 846848.CrossRefGoogle ScholarPubMed
Klemow, D., Einsphar, D., Brown, T. A., Flowers, C. H. & Skikne, B. S. (1990). Serum transferrin receptor measurements in hematologic malignancies. American Journal of Hematology 34, 193198.CrossRefGoogle ScholarPubMed
Kohgo, Y., Niitsu, Y., Nishisato, T., Kondo, H., Kato, J., Tsushima, N., Hirayama, M., Sasaki, K. & Urushizaki, I. (1988). Immunoreactive transferrin receptor in sera of pregnant women. Placenta 9, 523531.CrossRefGoogle ScholarPubMed
Kohgo, Y., Nishisato, T., Kondo, H., Tsushima, N., Niitsu, Y. & Urushizaki, I. (1986). Circulating transferrin receptor in human serum. British Journal of Haematology 64, 277281.CrossRefGoogle ScholarPubMed
Labbe, R. F. & Rettmer, R. L. (1989). Zinc protoporphyrin: a product of iron-deficient erythropoiesis. Seminars in Hematology 26, 4046.Google ScholarPubMed
Leggett, B. A., Brown, N. N., Bryant, S. J., Duplock, L., Powell, L. W. & Halliday, J. W. (1990). Factors affecting the concentrations of ferritin in serum in a healthy Australian population. Clinical Chemistry 36, 13501355.CrossRefGoogle Scholar
Lozoff, B. (1988). Behavioral alterations in iron deficiency. Advances in Pediatrics 35, 331359.CrossRefGoogle ScholarPubMed
Lozoff, B. (1989). Methodologic issues in studying behavioral effects of infant iron-deficiency anemia. American Journal of Clinical Nutrition 50, 641654.CrossRefGoogle ScholarPubMed
McClelland, A., Kühn, L. C. & Ruddle, F. H. (1984). The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence. Cell 39, 267274.CrossRefGoogle ScholarPubMed
McClure, S., Custer, E. & Bessman, J. D. (1985). Improved detection of early iron deficiency in nonanemic subjects. Journal of the American Medical Association 253, 10211023.CrossRefGoogle ScholarPubMed
Murphy, J. F., O'Riordan, J., Newcombe, R. G., Coles, E. C. & Pearson, J. F. (1986). Relation of haemoglobin levels in first and second trimesters to outcome of pregnancy. Lancet i, 992994.CrossRefGoogle Scholar
Omary, M. B. & Trowbridge, I. S. (1981). Biosynthesis of the human transferrin receptor in cultured cells. Journal of Biological Chemistry 256, 1288812892.CrossRefGoogle ScholarPubMed
Oski, F. A. & Honig, A. S. (1978). The effects of therapy on the developmental scores of iron-deficient infants. Journal of Pediatrics 92, 2125.CrossRefGoogle Scholar
Pilch, S. M. & Senti, F. R. [editors] (1984). Assessment of the Iron Nutritional Status of the U.S. Population Based on Data Collected in the Second National Health and Nutrition Examination Survey, 1976–1980. Bethesda, MD: FASED.Google Scholar
Piomelli, S., Davidow, D., Guinee, V. F., Young, P. & Gay, G. (1973). The FEP (free erythrocyte porphyrins) test: a screening micromethod for lead poisoning. Pediatrics 51, 254259.CrossRefGoogle Scholar
Pollitt, E., Hathirat, P., Kotchabhakdi, N. J., Missell, L. & Valyasevi, A. (1989). Iron deficiency and educational achievement in Thailand. American Journal of Clinical Nutrition 50, 687697.CrossRefGoogle ScholarPubMed
Schifman, R. B. & Rivers, S. L. (1987). Red blood cell zinc protoporphyrin to evaluate anemia risk in deferred blood donors. American Journal of Clinical Pathology 87, 511514.CrossRefGoogle ScholarPubMed
Seligman, P. A. (1983). Structure and function of the transferrin receptor. Progress in Hematology 13, 131147.Google ScholarPubMed
Shih, Y. J., Baynes, R. D., Hudson, B. G., Flowers, C. H., Skikne, B. S. & Cook, J. D. (1990). Serum transferrin is a truncated form of tissue receptor. Journal of Biological Chemistry 265, 1907719081.CrossRefGoogle ScholarPubMed
Skikne, B. S., Ferguson, B. J., Simpson, K., Baynes, R. D. & Cook, J. D. (1990 a). Serum transferin receptor distinguishes anemia of chronic disease from iron deficiency. Blood 76, 48a.Google Scholar
Skikne, B. S., Flowers, C. H. & Cook, J. D. (1990 b). Serum transferrin receptor: a quantitative measure of tissue iron deficiency. Blood 75, 18701876.CrossRefGoogle ScholarPubMed
Stevens, R. G., Jones, D. Y., Micozzi, M. S. & Taylor, P. R. (1988). Body iron stores and the risk of cancer. New England Journal of Medicine 319, 10471052.CrossRefGoogle ScholarPubMed
Vicente, C., Porto, G. & de Sousa, M. (1990). Method for establishing serum ferritin reference values depending on sex and age. Journal of Laboratory and Clinical Medicine 116, 779784.Google ScholarPubMed
Walter, T. (1989). Infancy: mental and motor development. American Journal of Clinical Nutrition 50, 655666.CrossRefGoogle ScholarPubMed
Ward, J. H. (1987). The structure, function, and regulation of transferrin receptors. Investigative Radiology 22, 7483.CrossRefGoogle ScholarPubMed
Worwood, M. (1986). Serum ferritin. Clinical Science 70, 215220.CrossRefGoogle ScholarPubMed
Worwood, M. (1990). Ferritin. Blood Reviews 4, 259269.CrossRefGoogle ScholarPubMed
Worwood, M., Thorpe, S. J., Heath, A., Flowers, C. H. & Cook, J. D. (1991). Stable lyophilised reagents for the serum ferritin assay. Clinical and Laboratory Haematology 13, 297305.CrossRefGoogle ScholarPubMed