Journal of Biological Chemistry
Volume 294, Issue 1, January 2019, Pages 195-209
Cell BiologyThe nucleosome remodeling and deacetylase complex protein CHD4 regulates neural differentiation of mouse embryonic stem cells by down-regulating p53
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embryonic stem cell
neurodifferentiation
nucleosome remodeling deacetylase (NuRD)
p53
protein degradation
chromodomain helicase DNA-binding protein 4 (CHD4)
lineage specification
methyl-CpG binding domain protein 3 (MBD3)
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This work was supported by grants from the Advanced Research and Development Programs for Medical Innovation from the Japan Agency for Medical Research and Development (AMED) (to E. N.). The authors declare that they have no conflicts of interest with the contents of this article.
This article contains Tables S1–S4.
The microarray data have been deposited in the National Center for Biotechnology Information Gene Expression Omnibus (GEO) under the accession number GSE114389.
© 2019 Hirota et al.