Journal of Biological Chemistry
Protein Structure and FoldingStructural Characterization of the Human Androgen Receptor Ligand-binding Domain Complexed with EM5744, a Rationally Designed Steroidal Ligand Bearing a Bulky Chain Directed toward Helix 12*
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The atomic coordinates and structure factors (code 2PNU) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
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This work was supported in part by Endorecherche Inc. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
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Recipient of a doctoral scholarship provided by the Fonds de la Recherche en Santé du Québec.
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Present address: Ottawa Institute of Systems Biology, 451 Smyth Rd., Ottawa, Ontario K1H 8M5, Canada.
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Present address: Synchrotron-SOLEIL, BP48 Saint Aubin, 91192 Gif-sur-Yvette, France.