Journal of Biological Chemistry
Volume 277, Issue 39, 27 September 2002, Pages 36521-36526
PROTEIN SYNTHESIS POST-TRANSLATION MODIFICATION AND DEGRADATIONPresenilin 1 Mutations Activate γ42-Secretase but Reciprocally Inhibit ε-Secretase Cleavage of Amyloid Precursor Protein (APP) and S3-Cleavage of Notch*
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Published, JBC Papers in Press, July 15, 2002, DOI 10.1074/jbc.M205093200
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This work was supported by grants from the Canadian Institutes of Health Research, the Canadian Genetic Disease Network, the Alzheimer Society of Ontario, the Howard Hughes Medical Institute, and the Scottish Rite Charitable Foundation.The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
© 2002 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.