Journal of Biological Chemistry
Volume 288, Issue 22, 31 May 2013, Pages 15699-15711
NeurobiologyMutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes: IMPLICATIONS FOR DISEASE SPREADING AND MOTOR NEURON PATHOLOGY IN AMYOTROPHIC LATERAL SCLEROSIS*
Under a Creative Commons license
open access
Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
Astrocytes
Exosomes
Proteomics
Superoxide Dismutase (SOD)
Disease Spreading
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This work is dedicated to the memory of our friend and colleague Francesco Gensano.
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This work was supported by the Telethon (Grants S01010 and TCR08002) (to V.B.), Cariplo (to V. B. and C. B.), Compagnia San Paolo (to V. B.), and Aldo e Cele Daccò Foundations (to V. B.) and the European Community's Health Seventh Framework Programme (FP7/2007–2013) under Grant Agreement 259867 (to V. B. and C. B.).
This article contains supplemental Table S1 and Figs. S1 and S2.
- 1
Both authors contributed equally to this work.
- 2
Recipient of a Leonardi Fellowship. Present address: Burke Medical Research Institute, Weill Medical College, Cornell University, Ithaca, NY.
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Recipient of a fellowship from the Vialli and Mauro Foundation for Research and Sport.
© 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.