Journal of Biological Chemistry
Volume 287, Issue 21, 18 May 2012, Pages 17530-17545
Signal TransductionStructure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling*
Under a Creative Commons license
open access
Acidosis
Lysosomes
mTOR Complex (mTORC)
Organellar pH Homeostasis
S6 Kinase
Cytoplasmic pH Homeostasis
Niclosamide
Cited by (0)
Supported by a Canadian Institute of Health Research postdoctoral fellowship.
- *
This work was supported in part by grants from the Canadian Breast Cancer Foundation (to M. R.) and from the Canadian Cancer Society (to N. S.).
This article contains supplemental Figs. 1–4 and Table 1.
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Present address: The Solomon H. Snyder Dept. of Neuroscience, The Johns Hopkins University School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.
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Present address: Neuroscience Group, Novartis Inst. for Biomedical Research, CH-4056 Basel, Switzerland.
© 2012 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.