Journal of Biological Chemistry
Volume 285, Issue 21, 21 May 2010, Pages 16286-16293
Gene RegulationPhosphorylation-induced Conformational Changes in the Retinoblastoma Protein Inhibit E2F Transactivation Domain Binding*
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Cdk (Cyclin-dependent Kinase)
Cell Cycle
E2F Transcription Factor
Protein Phosphorylation
Retinoblastoma (Rb)
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A Pew Scholar in the Biomedical Sciences, supported by The Pew Charitable Trusts.
- *
This work was supported, in whole or in part, by National Institutes of Health Grants CA132685 (to S. M. R.) and GM68933 (to support the Central California 900-MHz facility), and SS10-RR20939 (to support the University of California Santa Cruz mass spectrometry facility).
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. 1–3.
© 2010 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.