Journal of Biological Chemistry
Volume 272, Issue 10, 7 March 1997, Pages 6097-6100
CommunicationsThe Tuberous Sclerosis 2 Gene Product, Tuberin, Functions as a Rab5 GTPase Activating Protein (GAP) in Modulating Endocytosis*
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- *
This work was supported by National Institutes of Health Grant CA61889, American Cancer Society Grant CN-161, National Tuberous Sclerosis Association Grant 95-3, and an appropriation from the Commonwealth of Pennsylvania. The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement− in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
- ‡
These authors contributed equally to this work.
- 1
The abbreviations used are:
- TSC
tuberous sclerosis complex
- CHAPS
3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid
- PAGE
polyacrylamide gel electrophoresis
- GST
glutathione S-transferase
- GAP
GTPase activating protein
- HRP
horseradish peroxidase
- DTT
dithiothreitol.
© 1997 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.