Journal of Biological Chemistry
Volume 289, Issue 36, 5 September 2014, Pages 25101-25111
Molecular Bases of DiseaseNLRP3 Inflammasome Mediates Albumin-induced Renal Tubular Injury through Impaired Mitochondrial Function*
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open access
Cited by (0)
- *
This work was supported by National Basic Research Program of China 973 Program Grants 2012CB517602 and 2013CB530604; National Natural Science Foundation of China Grants 81325004, 81270797, and 81170635; Natural Science Foundation of Jiangsu Province Grant BK2012001, and Program for New Century Excellent Talents in University Grant NCET-12-0738.
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The abbreviations used are:
- ROS
reactive oxygen species
- CKD
chronic kidney disease
- mPTC
mouse proximal tubular cell
- mtDNA
mitochondrial DNA
- MMP
mitochondrial membrane potential
- qRT-PCR
quantitative real time PCR
- TUNEL
transferase dUTP nick end labeling
- MnTBAP
Mn(III)tetrakis (4-benzoic acid) porphyrin
- CsA
cyclosporin A
- Cyt C
cytochrome C
- α-SMA
α-smooth muscle actin.
© 2014 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.