Journal of Biological Chemistry
Volume 280, Issue 41, 14 October 2005, Pages 34956-34965
Enzyme Catalysis and RegulationStructural and Mechanistic Studies on Carboxymethylproline Synthase (CarB), a Unique Member of the Crotonase Superfamily Catalyzing the First Step in Carbapenem Biosynthesis*
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The atomic coordinates and structure factors (code 2A7K and 2A81) have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/).
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This work was supported by the European Union, Biotechnology and Biological Sciences Research Council, Wellcome Trust and Amura (for a CASE award to M. C. S.). The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. S1 and S2 and Schemes S1 and S2.
© 2005 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.