Life in the small intestine: the forgotten microbiome?
Erin R Shanahan A B C , Gerald Holtmann A and Mark Morrison B
+ Author Affiliations
- Author Affiliations
A Department of Gastroenterology and Hepatology, Princess Alexandra Hospital and Faculty of Medicine, The University of Queensland, Brisbane, Qld, Australia
B The University of Queensland Diamantina Institute, Brisbane, Qld, Australia
C Translational Research Institute, 37 Kent Street, Woolloongabba, Qld 4102, Australia. Tel: +61 7 3443 8022, Email: e.shanahan@uq.edu.au
Microbiology Australia 38(3) 116-121 https://doi.org/10.1071/MA17045
Published: 11 August 2017
Abstract
The gastrointestinal (GI) microbiota is now widely accepted to be an important modulator of our health and well-being. The microbes colonising the GI tract aid in promoting gut and immune homeostasis, while alterations in the composition and/or density of these microbes, often referred to as dysbiosis, have been implicated in many intestinal and extra-intestinal disorders. As a result, the GI microbiota is of increasing interest as a therapeutic target. This is particularly the case in the context of GI disorders linked to chronic inflammation of the mucosa. In this article, we focus on the small intestinal microbiota, which in many senses can be considered the ‘forgotten' gut microbiome.
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