Transactions of the Sixty-Ninth Annual Meeting of the Central Association of Obstetricians and GynecologistsPelvic organ prolapse in the women's health initiative: Gravity and gravidity☆,☆☆
Section snippets
Study population
The study population included women who enrolled in the Women's Health Initiative (WHI) Hormone Replacement Therapy Clinical Trial (n = 27,342 women). The WHI is a prospective study of 161,861 women aged 50 to 79 years after menopause in ≥1 of 3 clinical trials or an observational study who were enrolled from 1994 through 1998 in 40 clinical centers in the United States. The ethnic distribution includes a diverse population that is 18.3% minority, which represents major ethnic and racial groups
Results
Of the women with a uterus, 41.1% had some form of prolapse, with 34.3% having cystocele, 14.2% having uterine prolapse, and 18.6% having rectocele. Approximately 1 in 5 participants had prolapse at ≥2 sites. Almost 38% of women without a uterus had some form of prolapse, with 32.9% having cystocele and 18.3% having rectocele. The prevalence of uterine prolapse, cystocele, and rectocele by hysterectomy status is shown graphically in Fig 1.
Comment
This study establishes a very high prevalence of pelvic organ prolapse in this cohort of women after menopause. Cystocele was the most common form of prolapse and was present in more than one third of the women, regardless of uterine status. Pelvic organ prolapse was associated with multiple factors in this report, the strongest being parity. Although an increase in cystocele was seen with each subsequent birth, the strongest association was seen with first birth. Cystocele prevalence for women
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Cited by (0)
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Supported by National Institutes of Health contracts No. N01-WH-2-2110, N01-WH-3-2100, N01-WH-3-2101, N01-WH-3-2102, N01-WH-3-2105, N01-WH-3-2106, N01-WH-3-2108, N01-WH-3-2109, N01-WH-3-2110, N01-WH-3-2111, N01-WH-3-2112, N01-WH-3-2113, N01-WH-3-2115, N01-WH-3-2118, N01-WH-3-2119, N01-WH-3-2120, N01-WH-3-2122, N01-WH-4-2107, N01-WH-4-2108, N01-WH-4-2109, N01-WH-4-2110, N01-WH-4-2111, N01-WH-4-2112, N01-WH-4-2113, N01-WH-4-2114, N01-WH-4-2115, N01-WH-4-2116, N01-WH-4-2117, N01-WH-4-2118, N01-WH-4-2119, N01-WH-4-2120, N01-WH-4-2121, N01-WH-4-2122, N01-WH-4-2123, N01-WH-4-2124, N01-WH-4-2125, N01-WH-4-2126, N01-WH-4-2129, N01-WH-4-2130, N01-WH-4-2131, N01-WH-4-2132.
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Reprint requests: Susan L. Hendrix, DO, Department of Obstetrics and Gynecology, Wayne State University/Hutzel Hospital, 4707 St Antoine, Detroit, MI 48201. E-mail: [email protected]