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Skull Base 2007; 17(4): 239-246
DOI: 10.1055/s-2007-984489
CASE REPORT

Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Malignant Solitary Fibrous Tumor of the Nasal Cavity

Daniel M. Zeitler1 , 2 , Seth J. Kanowitz1 , 2 , Gady Har-El2 , 3 , 4
  • 1Department of Otolaryngology, New York University School of Medicine, New York, New York
  • 2Department of Otolaryngology-Head and Neck Surgery, Lenox Hill Hospital, New York, New York
  • 3Department of Otolaryngology, State University of New York-Downstate University, New York, New York
  • 4Department of Neurosurgery, State University of New York-Downstate University, New York, New York
Further Information

Publication History

Publication Date:
17 July 2007 (online)

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Commentary “Malignant Solitary Fibrous Tumor of the Nasal Cavity”Skull Base 2007; 17(04): 244-245
DOI: 10.1055/s-2007-984490

ABSTRACT

Solitary fibrous tumors (SFTs) are unusual mesenchymal tumors that were first described as primary spindle-cell neoplasms of the pleura. These tumors have been described in many other locations, including the urogenital system, orbit, mediastinum, and upper respiratory tract. Twenty-two cases of an SFT of the paranasal sinuses and nasal cavity have been reported, but none described a malignant SFT extending through the anterior skull base. A 70-year-old man had a 6-month history of unilateral left-sided epiphora and nasal obstruction. Computed tomography and magnetic resonance imaging showed a large left-sided nasal cavity mass with extension into the left extraconal orbit and intracranial extension through the left cribriform plate and ethmoid roof. The patient underwent preoperative embolization of the internal maxillary artery and a subsequent anterior craniofacial resection via a midfacial degloving approach and a left anterior craniotomy. Histopathological analysis of the specimen was consistent with a malignant SFT.

KEYWORDS

Solitary fibrous tumor - midfacial degloving - anterior skull base - nasal cavity - immunohistochemistry

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Daniel M ZeitlerM.D. 

550 First Ave., New Bellevue 5 East 5

New York, NY 10016

Email: dmz206@med.nyu.edu

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