Semin Thromb Hemost 2005; 31(3): 327-333
DOI: 10.1055/s-2005-872440
Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Fetal/Neonatal Outcome in Abruptio Placentae during Preterm Gestation

Yoshio Matsuda1 , 2 , Takatsugu Maeda1 , Satoshi Kouno1
  • 1Department of Obstetrics and Gynecology, Kagoshima City Hospital, Kagoshima, Japan
  • 2Associate Professor, Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan
Further Information

Publication History

Publication Date:
28 July 2005 (online)

ABSTRACT

The purpose of this study was to evaluate the fetal/neonatal outcome and to determine the important factors in that outcome, including the use of ultrasonography and fetal heart rate monitoring, in abruptio placentae during preterm gestation. A case-control study was performed using a logistic regression model. Adverse outcome was defined as neonatal death before hospital discharge or a diagnosis of cerebral palsy in surviving neonates. Stillbirth (group 1) occurred in eight of 50 cases of abruptio placentae (16%). Adverse outcome was seen in 11 survivors (11 of 42; 26.2%). The obstetrical disseminated intravascular coagulation (DIC) score in group 1 (11.8 ± 7.1) was higher than that in the adverse (5.7 ± 1.3) and satisfactory (5.3 ± 2.4) outcome groups. A low Apgar score (< 7) at 5 minutes (odds ratio, 19.8; 95% confidence interval, 2.0 to 197.8) was associated with increased risk of adverse outcome in the logistic regression model. Although the obstetrical DIC score was high and may reflect the severity of maternal complications in the stillbirth group, there were no typical ultrasonographic findings and fetal heart rate patterns in abruptio placentae during preterm gestation predicting adverse outcome among survivors.

REFERENCES

  • 1 Nelson K B, Ellenberg J H. Obstetric complications as risk factors for cerebral palsy or seizure disorders.  JAMA. 1984;  251 1843-1848
  • 2 Jaffe M H, Schoen W C, Silver T M, Bowerman R A, Stuck K J. Sonography of abruptio placentae.  AJR Am J Roentgenol. 1981;  137 1049-1054
  • 3 ACOG Technical Bulletin. Fetal heart rate patterns: monitoring, interpretation, and management, No. 207.  Int J Gynaecol Obstet. 1995;  51 65-74
  • 4 Freeman R K, Garite T J, Nageotte M P. Diagnosis and management of fetal distress in premature gestation. In: Freeman RK, Garite TJ, Nageotte MP Fetal Heart Rate Monitoring, 2nd ed. Baltimore; Williams & Wilikins 1991: 144
  • 5 Terao T, Maki M, Ikenoue T. A prospective study in 38 patients with abruptio placentae of 70 cases complicated by DIC.  Asia Oceania J Obstet Gynaecol. 1987;  13 1-13
  • 6 Kobayashi N, Maekawa T, Takada M, Tanaka H, Gonmori H. Criteria for diagnosis DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the research committee on DIC in Japan. In: Abe T, Yamanaka M Disseminated Intravascular Coagulation Tokyo, Japan; University of Tokyo Press 1983: 265-275
  • 7 Page E W. Abruptio placentae, dangers of delay in delivery.  Obstet Gynecol. 1954;  3 385-391
  • 8 Knab D R. Abruptio placentae. An assessment of the time and mode of delivery.  Obstet Gynecol. 1978;  52 625-629
  • 9 Ikenoue T, Matsuda Y, Kamitomo M, Hokanishi H. Combination therapy of intravenous ritodrine and magnesium sulfate to inhibit preterm labor.  Acta Obstet Gynaecol Jpn. 1989;  41 1972-1978
  • 10 Parer J T. Fetal heart rate. In: Creasy RK, Resnik R Maternal-Fetal Medicine. 4th ed. Philadelphia; Saunders 1999: 290
  • 11 Winkler C L, Hauth J C, Tucker J M, Owen J, Brumfield C G. Neonatal complications at term, as related to the degree of umbilical artery acidemia.  Am J Obstet Gynecol. 1991;  164 637-641
  • 12 Matsuda Y, Kouno S, Hiroyama Y et al.. Intrauterine infection, magnesium sulfate exposure and cerebral palsy in infants born between 26 and 30 weeks of gestation.  Eur J Obstet Gynecol Reprod Biol. 2000;  91 159-164
  • 13 Taylor D J, Howie P W, Davidson J et al.. Do pregnancy complications contribute to neurodevelopmental disability?.  Lancet. 1985;  1 713-716
  • 14 Beeby P J, Elliott E J, Henderson-Smart D J, Rieger I D. Predictive value of umbilical artery pH in preterm infants.  Arch Dis Child. 1994;  71 F93-F96
  • 15 Spinillo A, Fassi E, Stronati M, Ometto A, Capuzzo E, Guaschino S. Early morbidity and neurodevelopmental outcome in low-birth-weight infants born after third trimester bleeding.  Am J Perinatol. 1994;  11 85-90

Yoshio MatsudaM.D. 

Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Kawada-cho

8-1, Shinjuku-ku, Tokyo 162-8666, Japan

Email: ymatsuda@obgy.twmu.ac.jp

    >