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Planta Med 2003; 69(10): 959-961
DOI: 10.1055/s-2003-45110
Letter
© Georg Thieme Verlag Stuttgart · New York

Lignan Profiles of Indoor-Cultivated Anthriscus sylvestris

Albert Koulman1 , Sieb Batterman1 , Freeke M. S. van Putten1 , Rein Bos1 , Wim J. Quax1
  • 1Department of Pharmaceutical Biology, GUIDE (Groningen University Institute for Drug Exploration), University of Groningen, Groningen, The Netherlands
This project was partly sponsored by the EU; BIO4-CT98-0461 LIGNOCANCER; Plant Cell Factories as a Source of Anti-Cancer Lignans
Further Information

Publication History

Received: February 13, 2003

Accepted: July 12, 2003

Publication Date:
02 December 2003 (online)

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Abstract

In a previous study we have shown that different populations of Anthriscus sylvestris (L.) Hoffm. (Apiaceae) yield significantly different lignan profiles. In this study we collected the seeds of A. sylvestris from 4 locations, one in England and three in The Netherlands. The seeds germinated and were grown under identical laboratory conditions. After 5 months the plants were harvested and the lignan profile in the roots and aerial parts was analysed using GC-MS. The plants from the seeds of the 4 locations showed several significant phenotypic differences in, for instance, dry-weight. However the 4 groups did not differ significantly in their lignan profile in their roots. The lignans in the roots of A. sylvestris, deoxypodophyllotoxin, yatein and anhydropodorhizol reached, on average, equal amounts in all 4 groups. Within the 4 groups, however, a large quantitative variation in lignan profile between the individual plants was observed, pointing to within-population genetic differences between individual plants.

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Dr. Rein Bos

Department of Pharmaceutical Biology

GUIDE (Groningen University Institute for Drug Exploration)

University of Groningen

A. Deusinglaan 1

9713 AV Groningen

The Netherlands

Phone: +31-50-3633354

Fax: +31-50-3633000

Email: R.Bos@farm.rug.nl

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