Asymmetric Synthesis of 1-Aminopentadecane-3,5,7,9,11,13,15-heptols and of 1,15-Diaminopentadecane-3,5,7,9,11,13-hexols and Derivatives

 

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Abstract

Starting from 2,2′-methylenedifuran, enantiomeri­cally enriched (98%) (3R,5S,7R,9S,11R,13R)- and (3R,5S,7S,9R,11R,13R)-15-amino-5,7,9,11-tetrahydroxy-3,13-bis-(4-methoxybenzoyloxy)pentadec-1-yl) pivalate were prepared as well as (3R,5R,7R,9R,11S,13S)-1,15-diamino-5,7,9,11-tetra­hydroxypentadeca-3,13-diyl bis(4-methoxybenzoate) and (3R,5S,7S,9S,11R,13S)-1,15-diaminopentadecane-3,5,7,9,11,13-hexol.

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