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Klin Padiatr 2000; 212(1): 22-25
DOI: 10.1055/s-2000-9646
ORIGINALARBEIT

Georg Thieme Verlag Stuttgart · New York

Diabetes mellitus Typ I, Zöliakie und Imerslund-Gräsbeck-Syndrom: nur eine ungewöhnliche Kombination seltener Erkrankungen?

Diabetes mellitus type I, coeliac disease and Imerslund-Graesbeck-syndrome: simply an unusual combination of rare diseases?Antje  Schröder, Olaf  Witt, Stefan  Eber
  • Universitätsklinik Göttingen
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Publication History

Publication Date:
31 December 2000 (online)

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Zusammenfassung.

Wir beschreiben eine Patientin, die im Alter von 3 Jahren an einem Diabetes mellitus Typ I erkrankte, im Alter von 10 Jahren wurde eine oligosymptomatische Zöliakie und kurze Zeit später eine Vitamin-B12-Mangelanämie (Imerslund-Gräsbeck-Syndrom) diagnostiziert. Die 3 Jahre jüngere Schwester erkrankte mit 11 Jahren ebenfalls an einer Vitamin-B12-Mangelanämie, die als Imerslund-Gräsbeck-Syndrom klassifiziert wurde. Diese ungewöhnliche, bisher nicht beschriebene, Assoziation seltener Erkrankungen läßt an eine gemeinsame autoimmune Ätiologie denken.

We describe the clinical course of a girl with onset of type I diabetes mellitus at the age of 3 years. At the age of 10, coeliac disease and shortly thereafter a vitamin B12 deficiency anemia (Imerslund-Graesbeck-syndrome) was diagnosed. Her younger sister also suffered from Imerslund-Graesbeck-syndrome when she was 11 year old. This unusual, so far not described association of rare diseases suggests a common autoimmune etiology.

Schlüsselwörter:

Diabetes mellitus - Zöliakie - Imerslund-Gräsbeck-Syndrom

Key words:

Diabetes mellitus - coeliac disease - Imerslund-Graesbeck-syndrome

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Dr. Antje Schröder

Kinderkrankenhaus auf der Bult

Janusz-Korczak-Allee 12

D-30173 Hannover

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