CC BY-NC-ND 4.0 · Laryngorhinootologie 2022; 101(S 02): S236
DOI: 10.1055/s-0042-1746499
Abstracts | DGHNOKHC
Imaging / Sonography: Neck

Characterization of cervical lymph nodes by using multiparametric ultrasound

Katharina Margherita Wakonig
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte und Virchow Klinikum, Berlin
,
Markus Herbert Lerchbaumer
2   Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Radiologie, Campus Charité Mitte, Berlin
,
Philipp Arens
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte und Virchow Klinikum, Berlin
,
Thomas Fischer
2   Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Radiologie, Campus Charité Mitte, Berlin
,
Heidi Olze
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte und Virchow Klinikum, Berlin
,
Steffen Dommerich
1   Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Klinik für Hals-, Nasen-, Ohrenheilkunde, Campus Charité Mitte und Virchow Klinikum, Berlin
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Introduction Enlarged cervical lymph nodes (CLN) should be evaluated to differentiate between malign or benign causes. Especially patients who suffered from a malignant disease in the head-and-neck area need to get a regular check on CLN to rule out metastasis. Ultrasound (US) is the imaging modality of choice by using established criteria for B-Mode and color duplex imaging to differentiate reactive from metastatic nodes. In case of suspicious CLN a histological evaluation is recommended. This study aims to ameliorate the preoperative differentiation of malign and benign CLN by using multiparametric ultrasound (mpUS).

Material and Methods In addition to B-mode US and color duplex imaging, shear-wave elastography (SWE) and contrast enhanced ultrasound (CEUS) were applied for all patients before surgery, 1.2 ml of the contrast enhancing agent SonoVue​ were applied systemically. Raw data (90 seconds video loop) were quantified by using the postprocessing software VueBox​ (Braco) and the resulting CEUS time-intensity-curves were analyzed.

Results The SWE-analysis of 82 CLN (26 benign, 57 malign) showed a significant difference between benign and malign nodes (p< 0.05). No significant CEUS differentiation between malign and benign CLN were retrieved (p >0.05).

Discussion Our results indicate SWE to be a useful non-invasive additional diagnostic tool to ameliorate the sonographic differentiation of suspicious CLN for the purposes of primary diagnosis as well as oncological aftercare.



Publication History

Article published online:
24 May 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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