Geburtshilfe Frauenheilkd 2020; 80(06): 14
DOI: 10.1055/s-0040-1713225
Abstracts Geburtshilfe & Fetomaternale Medizin Jahrestagung Graz

Preliminary Results from the Nationwide Austrian Register for Reproduction and Rheumatic Disease (RhePro Register)

K Rosta
1   Abteilung für Geburtshilfe und fetomaternale Medizin, Universitätsklinik für Frauenheilkunde Medizinische Universität Wien
,
D Mrak
2   Universitätsklinik für Innere Medizin III, Klinische Abteilung für Rheumatologie, Medizinische Universität Wien
,
N Valenta
1   Abteilung für Geburtshilfe und fetomaternale Medizin, Universitätsklinik für Frauenheilkunde Medizinische Universität Wien
,
T Stamm
3   Zentrum für Medizinische Statistik, Informatik und Intelligente Systeme, Medizinische Universität Wien
,
V Ritschl
3   Zentrum für Medizinische Statistik, Informatik und Intelligente Systeme, Medizinische Universität Wien
,
P Husslein
1   Abteilung für Geburtshilfe und fetomaternale Medizin, Universitätsklinik für Frauenheilkunde Medizinische Universität Wien
,
A Puchner
2   Universitätsklinik für Innere Medizin III, Klinische Abteilung für Rheumatologie, Medizinische Universität Wien
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Background: Data is limited regarding pregnancies and family planning with inflammatory rheumatic diseases. In May 2017, in the hope to collect more experience and data in this topic, the nationwide Austrian Register for Reproduction and Rheumatic disease (RhePro Register) was established at the Medical University of Vienna.

Methods: The RhePro Register is a prospective nationwide, web-based longitudinal observational cohort study. Pregnant patients with confirmed diagnosis of inflammatory rheumatic disease are eligible to be enrolled until the 20th week of pregnancy or patients who wish to conceive. Clinical and laboratory course of rheumatic disease, the course of pregnancy, maternal and fetal complications during and after pregnancy and information of pharmaceutical treatment throughout the pregnancy and 3 years postpartal will be documented and collected. The collected data is pseudoanonymized and data handling is conform with the data protection policy.

Results: The RhePro Register started on 15th of May 2017. Up to now there are 6 recruiting centers. Until the end of January 2018, 89 patients were recruited. 36 pregnant women delivered their children, 17 women are currently pregnant, and 36 women are in praeconceptional care. Of these patients 31 suffered from systemic lupus erythematosus, 11 from Sjögrens syndrome, 7 had other connective tissue diseases, 22 rheumatoid arthritis, 10 spondyloarthritis, 2 juvenile idiopathic arthritis, 2 psoriatic arthritis, and 3 systemic vasculitis. Average birthweight of the newborn was 2895 gr, average gestations week at delivery was 38 weeks. 9/36 (25%) of the newborn were either small for gestational age (n = 7 SGA) or had an intrauterine growth restriction (n = 2 IUGR) and 75% of the newborn were appropriate for gestational age (AGA) at delivery. Pregnancy complications included 1 HELLP syndrome, 6 patients experienced preterm delivery before gestational week 37, one patient had a postpartal deep venous thrombosis, 6 newborn were admitted to the neonatal intensive care unit postpartal, one child had a complex heart malformation.

Conclusions: The Austrian RhePro Register is launched. We hope to contribute to the present knowledge of patients with inflammatory rheumatic disease and pregnancy or present family planning. We hope to be able to include the results for 2019 in this abstract, this is being currently processed through RDA.



Publication History

Article published online:
02 June 2020

Georg Thieme Verlag KG
Stuttgart · New York