Thromb Haemost 1994; 72(05): 783-784
DOI: 10.1055/s-0038-1648959
Letter to the Editor
Schattauer GmbH Stuttgart

Evolution of Antibodies Anti-PF4/heparin in a Patient with a History of Heparin-induced Thrombocytopenia Reexposed to Heparin

Y Cadroy
1   Laboratoire d’Hématologie, Hôpital Purpan, Toulouse, France
,
J Amiral
2   Serbio Laboratories, Genevilliers, France
,
H Raynaud
3   Clinique Pasteur, Toulouse, France
,
P Brunel
3   Clinique Pasteur, Toulouse, France
,
A Mazaleyrat
3   Clinique Pasteur, Toulouse, France
,
M Sauer
3   Clinique Pasteur, Toulouse, France
,
P Sié
1   Laboratoire d’Hématologie, Hôpital Purpan, Toulouse, France
› Author Affiliations
Further Information

Publication History

Received 03 June 1994

Accepted after revision 29 July 1994

Publication Date:
06 July 2018 (online)

 
  • References

  • 1 Greinacher A, Potzsch B, Amiral J, Dummel V, Eichner A, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-Heparin complex as the major antigen. Thromb Haemost 1994; 71: 247-251
  • 2 Amiral J, Bridey F, Dreyfus M, Vissac AM, Freyssinaud E, Wolf M, Meyer D. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost 1992; 68: 95-96
  • 3 Magnani HN. Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with Orgaran (Org 10172). Thromb Haemost 1993; 70: 554-561