Thromb Haemost 2000; 84(04): 736-737
DOI: 10.1055/s-0037-1614104
Letters to the Editor
Schattauer GmbH

Is there a Role for Genetic Polymorphism of C677T Methylenetetrahydrofolate Reductase (MTHFR) in Buerger’s Disease?

T. Kawasaki
1   From the division of Vascular Surgery, Department of Surgery, Osaka University Hospital, Japan
,
H. Fujimura
1   From the division of Vascular Surgery, Department of Surgery, Osaka University Hospital, Japan
,
E. Kakinoki
2   Kozu Hospital, Japan
,
A. Uemichi
2   Kozu Hospital, Japan
,
T. Miyata
3   National Cardiovascular Center Research Institute, Osaka, Japan
› Author Affiliations
Further Information

Publication History

Received 18 April 2000

Accepted 20 April 2000

Publication Date:
11 December 2017 (online)

 

 
  • References

  • 1 Graham IM, Daly LE, Refsum HM. et al. Plasma homocysteine as a risk factor for vascular disease: The European Concerted Action Project. JAMA 1997; 277: 1775-81.
  • 2 Frosst P, Blom HJ, Milos R. et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995; 10: 111-3.
  • 3 Piyathilake CJ, Macaluso M, Hine RJ, Richards EW, Krumdieck CL. Local and systemic effects of cigarette smoking on folate and vitamine B12. Am J Clin Nutr 1994; 60: 559-66.
  • 4 Shionoya S. Buerger’s disease: diagnosis and management. Cardiovasc Surg 1993; 01: 207-14.
  • 5 Fujimura H, Kawasaki T, Sakata T, Sakata T, Ariyoshi H, Kato H, Monden M, Miyata T. Common C677T polymorphism in the methylenetetrahydrofolate reductase gene increases the risk for deep vein thrombosis in patients with predisposition to thrombophilia. Thrombos Res 2000; 98: 1-8.