Semin Plast Surg 2014; 28(04): 199-206
DOI: 10.1055/s-0034-1390173
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Neonatal Mandibular Distraction Osteogenesis

Roberto L. Flores
1   Department of Plastic Surgery, NYU Langone Medical Center, New York, New York
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Publikationsdatum:
04. November 2014 (online)

Abstract

Mandibular distraction has revolutionized the treatment of Robin sequence associated with severe airway obstruction. The distraction technique remains the only intervention that directly corrects mandibular hypoplasia and the retropositioned tongue, providing efficient relief of airway stenosis. Multiple studies have demonstrated the efficacy of distraction in avoiding tracheostomy and decreasing the severity airway obstruction in this patient population. The benefit to avoiding tracheostomy and relieving airway obstruction is superior to that of tongue–lip adhesion. It is, therefore, not surprising that mandibular distraction has become the first-line intervention at many centers for the surgical treatment of Robin sequence. The complication profile associated with mandibular distraction appears low; the most common complication is infection, which can be treated by antibiotics alone. The severity of airway obstruction can be quantified by polysomnogram: This tool has become one of the most widely used objective metrics in the Robin sequence population. Therefore indications for surgery, timing of palatoplasty and long-term assessment of airway function should be performed in conjunction with sleep study analysis. The effects of mandibular lengthening on feeding difficulty in Robin sequence patient remains a topic of controversy. Studies have demonstrated conflicting results: This can be an area of future study. Agreed-upon indications for surgery and definitive protocols of care have yet to be formulized; future research should focus on achieving these goals. Such studies would require agreed-upon terminology for Robin sequence, an increase in comparative and prospective analysis, and the use of quantifiable metrics of clinical results.

 
  • References

  • 1 Robin P. LaGlossoptosis son diagnostic, ses consequences, son traitment. Bulletin de l'Academie National de Medecine, Paris; 1923
  • 2 Printzlau A, Andersen M. Pierre Robin sequence in Denmark: a retrospective population-based epidemiological study. Cleft Palate Craniofac J 2004; 41 (1) 47-52
  • 3 Holder-Espinasse M, Abadie V, Cormier-Daire V , et al. Pierre Robin sequence: a series of 117 consecutive cases. J Pediatr 2001; 139 (4) 588-590
  • 4 Latham RA. The pathogenesis of cleft palate associated with the Pierre Robin syndrome. An analysis of a seventeen-week human foetus. Br J Plast Surg 1966; 19 (3) 205-214
  • 5 Murage KP, Tholpady SS, Friel M, Havlik RJ, Flores RL. Outcomes analysis of mandibular distraction osteogenesis for the treatment of Pierre Robin sequence. Plast Reconstr Surg 2013; 132 (2) 419-421
  • 6 Caouette-Laberge L, Bayet B, Larocque Y. The Pierre Robin sequence: review of 125 cases and evolution of treatment modalities. Plast Reconstr Surg 1994; 93 (5) 934-942
  • 7 Singer L, Sidoti EJ. Pediatric management of Robin sequence. Cleft Palate Craniofac J 1992; 29 (3) 220-223
  • 8 Glander II K, Cisneros GJ. Comparison of the craniofacial characteristics of two syndromes associated with the Pierre Robin sequence. Cleft Palate Craniofac J 1992; 29 (3) 210-219
  • 9 Hoffman S, Kahn S, Seitchik M. Late problems in the management of the Pierre Robin syndrome. Plast Reconstr Surg 1965; 35: 504-511
  • 10 Parsons RW, Smith DJ. Rule of thumb criteria for tongue-lip adhesion in Pierre Robin anomalad. Plast Reconstr Surg 1982; 70 (2) 210-212
  • 11 Randall P. The Robin sequence: Micrognathia and glossoptosis with airway obstruction. Philadelphia, PA: Saunders; 1990
  • 12 Dykes EH, Raine PA, Arthur DS, Drainer IK, Young DG. Pierre Robin syndrome and pulmonary hypertension. J Pediatr Surg 1985; 20 (1) 49-52
  • 13 Sheffield LJ, Reiss JA, Strohm K, Gilding M. A genetic follow-up study of 64 patients with the Pierre Robin complex. Am J Med Genet 1987; 28 (1) 25-36
  • 14 Jolleys A. Micrognathos: a review of 38 cases treated in the newborn period. J Pediatr Surg 1966; 1 (5) 460-465
  • 15 Marques IL, de Sousa TV, Carneiro AF, Peres SP, Barbieri MA, Bettiol H. [Robin sequence: a single treatment protocol]. [Article in Portuguese] J Pediatr (Rio J) 2005; 81 (1) 14-22
  • 16 Smith MC, Senders CW. Prognosis of airway obstruction and feeding difficulty in the Robin sequence. Int J Pediatr Otorhinolaryngol 2006; 70 (2) 319-324
  • 17 Bush PG, Williams AJ. Incidence of the Robin aAnomalad (Pierre Robin syndrome). Br J Plast Surg 1983; 36 (4) 434-437
  • 18 Evans AK, Rahbar R, Rogers GF, Mulliken JB, Volk MS. Robin sequence: a retrospective review of 115 patients. Int J Pediatr Otorhinolaryngol 2006; 70 (6) 973-980
  • 19 Shprintzen RJ, Singer L. Upper airway obstruction and the Robin sequence. Int Anesthesiol Clin 1992; 30 (4) 109-114
  • 20 Cohen Jr MM. The Robin anomalad - its nonspecificity and associated syndromes. J Oral Surg 1976; 34 (7) 587-593
  • 21 Argamaso RV. Glossopexy for upper airway obstruction in Robin sequence. Cleft Palate Craniofac J 1992; 29 (3) 232-238
  • 22 Kirschner RE, Low DW, Randall P , et al. Surgical airway management in Pierre Robin sequence: is there a role for tongue-lip adhesion?. Cleft Palate Craniofac J 2003; 40 (1) 13-18
  • 23 Schaefer RB, Stadler III JA, Gosain AK. To distract or not to distract: an algorithm for airway management in isolated Pierre Robin sequence. Plast Reconstr Surg 2004; 113 (4) 1113-1125
  • 24 Guilleminault C, Simmons FB, Motta J , et al. Obstructive sleep apnea syndrome and tracheostomy. Long-term follow-up experience. Arch Intern Med 1981; 141 (8) 985-988
  • 25 Sasaki CT, Horiuchi M, Koss N. Tracheostomy-related subglottic stenosis: bacteriologic pathogenesis. Laryngoscope 1979; 89 (6 Pt 1) 857-865
  • 26 Zeitouni A, Manoukian J. Tracheotomy in the first year of life. J Otolaryngol 1993; 22 (6) 431-434
  • 27 Arola MK. Tracheostomy and its complications. A retrospective study of 794 tracheostomized patients. Ann Chir Gynaecol 1981; 70 (3) 96-106
  • 28 Singer LT, Kercsmar C, Legris G, Orlowski JP, Hill BP, Doershuk C. Developmental sequelae of long-term infant tracheostomy. Dev Med Child Neurol 1989; 31 (2) 224-230
  • 29 Tomaski SM, Zalzal GH, Saal HM. Airway obstruction in the Pierre Robin sequence. Laryngoscope 1995; 105 (2) 111-114
  • 30 Kohan E, Hazany S, Roostaeian J , et al. Economic advantages to a distraction decision tree model for management of neonatal upper airway obstruction. Plast Reconstr Surg 2010; 126 (5) 1652-1664
  • 31 Shukowsky WP. Aetiologie des stridor inspiratorius congenitus. Jahrbuche fiir Kinderheilk 1911; 73: 459-474
  • 32 Douglas B. The treatment of micrognathia associated with obstruction by a plastic procedure. Plast Reconstr Surg (1946) 1946; 1 (3) 300-308
  • 33 Oeconomopoulos CT. The value of glossopexy in Pierre-Robin syndrome. N Engl J Med 1960; 262: 1267-1268
  • 34 Rogers GF, Murthy AS, LaBrie RA, Mulliken JB. The GILLS score: part I. Patient selection for tongue-lip adhesion in Robin sequence. Plast Reconstr Surg 2011; 128 (1) 243-251
  • 35 Denny AD, Amm CA, Schaefer RB. Outcomes of tongue-lip adhesion for neonatal respiratory distress caused by Pierre Robin sequence. J Craniofac Surg 2004; 15 (5) 819-823
  • 36 Huang F, Lo LJ, Chen YR, Yang JC, Niu CK, Chung MY. Tongue-lip adhesion in the management of Pierre Robin sequence with airway obstruction: technique and outcome. Chang Gung Med J 2005; 28 (2) 90-96
  • 37 Denny AD, Talisman R, Hanson PR, Recinos RF. Mandibular distraction osteogenesis in very young patients to correct airway obstruction. Plast Reconstr Surg 2001; 108 (2) 302-311
  • 38 Denny AD. Distraction osteogenesis in Pierre Robin neonates with airway obstruction. Clin Plast Surg 2004; 31 (2) 221-229
  • 39 Hoffman W. Outcome of tongue-lip plication in patients with severe Pierre Robin sequence. J Craniofac Surg 2003; 14 (5) 602-608
  • 40 McCarthy JG, Schreiber J, Karp N, Thorne CH, Grayson BH. Lengthening the human mandible by gradual distraction. Plast Reconstr Surg 1992; 89 (1) 1-8 , discussion 9–10
  • 41 Monasterio FO, Molina F, Berlanga F , et al. Swallowing disorders in Pierre Robin sequence: its correction by distraction. J Craniofac Surg 2004; 15 (6) 934-941
  • 42 Williams JK, Maull D, Grayson BH, Longaker MT, McCarthy JG. Early decannulation with bilateral mandibular distraction for tracheostomy-dependent patients. Plast Reconstr Surg 1999; 103 (1) 48-57 ; discussion 58–49
  • 43 Denny A, Kalantarian B. Mandibular distraction in neonates: a strategy to avoid tracheostomy. Plast Reconstr Surg 2002; 109 (3) ):896–904;discussion 905–896
  • 44 Genecov DG, Barceló CR, Steinberg D, Trone T, Sperry E. Clinical experience with the application of distraction osteogenesis for airway obstruction. J Craniofac Surg 2009; 20 (Suppl. 02) 1817-1821
  • 45 Lam DJ, Tabangin ME, Shikary TA , et al. Outcomes of mandibular distraction osteogenesis in the treatment of severe micrognathia. JAMA Otolaryngol Head Neck Surg 2014; 140 (4) 338-345
  • 46 Andrews BT, Fan KL, Roostaeian J, Federico C, Bradley JP. Incidence of concomitant airway anomalies when using the University of California, Los Angeles, protocol for neonatal mandibular distraction. Plast Reconstr Surg 2013; 131 (5) 1116-1123
  • 47 Cruz MJ, Kerschner JE, Beste DJ, Conley SF. Pierre Robin sequences: secondary respiratory difficulties and intrinsic feeding abnormalities. Laryngoscope 1999; 109 (10) 1632-1636
  • 48 Bookman LB, Melton KR, Pan BS , et al. Neonates with tongue-based airway obstruction: a systematic review. Otolaryngol Head Neck Surg 2012; 146 (1) 8-18
  • 49 Flores RL, Tholpady SS, Sati S , et al. The surgical correction of Pierre Robin sequence: mandibular distraction osteogenesis versus tongue-lip adhesion. Plast Reconstr Surg 2014; 133 (6) 1433-1439
  • 50 Lidsky ME, Lander TA, Sidman JD. Resolving feeding difficulties with early airway intervention in Pierre Robin sequence. Laryngoscope 2008; 118 (1) 120-123
  • 51 Spring MA, Mount DL. Pediatric feeding disorder and growth decline following mandibular distraction osteogenesis. Plast Reconstr Surg 2006; 118 (2) 476-482
  • 52 Reid J, Kilpatrick N, Reilly S. A prospective, longitudinal study of feeding skills in a cohort of babies with cleft conditions. Cleft Palate Craniofac J 2006; 43 (6) 702-709
  • 53 Marques IL, Bettiol H, de Souza L, Barbieri MA, Bachega MI. Longitudinal study of the growth of infants with isolated Robin sequence considered being severe cases. Acta Paediatr 2008; 97 (3) 371-375
  • 54 Flores RL, Murage K, Tholpady SS. Incidence of concomitant airway anomalies when using the University of California, Los Angeles, protocol for neonatal mandibular distraction. Plast Reconstr Surg 2013; 132 (6) 1071e-1072e
  • 55 Murage KP, Costa MA, Friel MT, Havlik RJ, Tholpady SS, Flores RL. Complications associated with neonatal mandibular distraction osteogenesis in the treatment of Robin sequence. J Craniofac Surg 2014; 25 (2) 383-387
  • 56 Bull MJ, Givan DC, Sadove AM, Bixler D, Hearn D. Improved outcome in Pierre Robin sequence: effect of multidisciplinary evaluation and management. Pediatrics 1990; 86 (2) 294-301
  • 57 Hammoudeh J, Bindingnavele VK, Davis B , et al. Neonatal and infant mandibular distraction as an alternative to tracheostomy in severe obstructive sleep apnea. Cleft Palate Craniofac J 2012; 49 (1) 32-38
  • 58 Burstein FD, Williams JK. Mandibular distraction osteogenesis in Pierre Robin sequence: application of a new internal single-stage resorbable device. Plast Reconstr Surg 2005; 115 (1) 61-67 , discussion 68–69
  • 59 Davidson EH, Brown D, Shetye PR , et al. The evolution of mandibular distraction: device selection. Plast Reconstr Surg 2010; 126 (6) 2061-2070
  • 60 Morovic CG, Monasterio L. Distraction osteogenesis for obstructive apneas in patients with congenital craniofacial malformations. Plast Reconstr Surg 2000; 105 (7) 2324-2330
  • 61 Wootten CT, French LC, Thomas RG, Neblett III WW, Werkhaven JA, Cofer SA. Tracheotomy in the first year of life: outcomes in term infants, the Vanderbilt experience. Otolaryngol Head Neck Surg 2006; 134 (3) 365-369
  • 62 Robison JG, Otteson TD. Increased prevalence of obstructive sleep apnea in patients with cleft palate. Arch Otolaryngol–Head & Neck Surgery 2011; 137 (3) 269-274
  • 63 Henriksson TG, Skoog VT. Identification of children at high anaesthetic risk at the time of primary palatoplasty. Scand J Plast Reconstr Surg Hand Surg 2001; 35 (2) 177-182
  • 64 Arteau-Gauthier I, Leclerc JE, Godbout A. Can we predict a difficult intubation in cleft lip/palate patients?. J Otolaryngol Head Neck Surg 2011; 40 (5) 413-419
  • 65 Lehman JA, Fishman JR, Neiman GS. Treatment of cleft palate associated with Robin sequence: appraisal of risk factors. Cleft Palate Craniofac J 1995; 32 (1) 25-29
  • 66 Antony AK, Sloan GM. Airway obstruction following palatoplasty: analysis of 247 consecutive operations. Cleft Palate Craniofac J 2002; 39 (2) 145-148