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Aktuelle Dermatologie 2012; 38(4): 138-146
DOI: 10.1055/s-0031-1291729
DOI: 10.1055/s-0031-1291729
Fort- und Weiterbildung
© Georg Thieme Verlag KG Stuttgart · New York
Grundlagen der Fototherapie
Basic Principles of PhototherapyFurther Information
Publication History
Publication Date:
02 April 2012 (online)
Lernziele
Kenntnisse im Bereich Fototherapie:
Grundlagen und Wirkmechanismen Indikationen Durchführung der einzelnen Fototherapiemodalitäten Unerwünschte Wirkungen der Fototherapie
Literatur
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- 2 Berneburg M, Lehmann A R. Xeroderma pigmentosum and related disorders: defects in DNA repair and transcription. Adv Genet. 2001; 43 71-102
- 3 Kulms D, Schwarz T. Molecular mechanisms of UV-induced apoptosis. Photodermatol Photoimmunol Photomed. 2000; 16 195-201
- 4 Schwarz T. The dark and the sunny sides of UVR-induced immunosuppression: photobiology revisited. J Invest Dermatol. 2010; 130 49-51
- 5 Wlascheck M, Heinen G, Poswig A et al. UVA-induced autocrine stimulation of fibroblasts derived collagenase/MMP1 by interrelated loops of interleukin-1 and interleukin-6. Photobiol. 1994; 59 550-556
- 6 Berneburg M, Gollnick E, Herzinger T et al. S1-Leitlinie Empfehlungen zur UV-Phototherapie und Photochemotherapie. Im Internet: http://www.awmf.org/uploads/tx_szleitlinien/013 – 029.pdf Stand: 1.12.2009
- 7 Storbeck H, Hölzle E, Schürer N et al. Narrow-band UVB (311 nm) versus conventional broad-band UVB with and without dithranol in phototherapy for psoriasis. J Am Acad Dermatol. 1993; 28 227-231
- 8 Hudson-Peacock M J, Diffey B L, Farr P M. Narrow-band UVB phototherapy for severe atopic dermatitis. Br J Dermatol. 1996; 135 332
- 9 Reynolds N J, Franklin V, Gray J C et al. Narrow-band ultraviolet B and broad-band ultraviolet A phototherapy in adult atopic eczema: a randomized controlled trial. Lancet. 2001; 357 2012-2016
- 10 Dummer R, Ivanova K, Scheidegger E P et al. Clinical and therapeutic aspects of polymorphous light eruption. Dermatology. 2003; 207 93-95
- 11 Njoo M D, Bos J D, Westerhof W. Treatment of generalized vitiligo in children with narrow-band (TL-01) UVB radiation. J Am Acad Dermatol. 2000; 42 245-253
- 12 Mutzhas M F, Hölzle E, Hofmann C et al. A new apparatus with high radiation energy between 320 – 460 nm: physical description and dermatological applications. J Invest Dermatol. 1981; 76 42-47
- 13 Krutmann J, Schöpf E. High-dose UVA 1 phototherapy: a novel and highly effective approach for the treatment of acute exacerbation of atopic dermatitis. Acta Derm Venereol Suppl (Stockh). 1992; 176 120-122
- 14 Kerscher M, Dirschka T, Volkenandt M. Treatment of localised scleroderma by UVA1 phototherapy. Lancet. 1995; 346 1166
- 15 Kerscher M, Volkenandt M, Meurer M et al. PUVA-bath photochemotherapy of lichen planus. Arch Dermatol. 1995; 131 1210-1211
- 16 Schwarz T, Rütter A, Hawk J. Phototherapy and photochemotherapy: less common indications for its use.. In: Krutmann J, Hönigsmann H, Elmets C A, Bergstresser P R, eds Dermatological phototherapy and photodiagnostic methods.. Berlin: Springer; 2001: 179-197
- 17 Radakovic S, Seeber A, Hönigsmann H et al. Failure of short-term psorelen and ultraviolet A light maintenance treatment to prevent early relapse in patients with chronic recurring plaque-type psoriasis. Photodermatol Photoimmunol Photomed. 2009; 25 90-93
- 18 Stern R S, Lunder E J. Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA). A meta-analysis. Arch Dermatol. 1998; 134 1582-1585
- 19 Stern R S, Nichols K T, Vakeva L H. Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA). N Engl J Med. 1997; 336 1041-1045
- 20 Weischer M, Blum A, Eberhard F et al. No evidence for increased skin cancer risk in psoriasis patients treated with broadband or narrowband UVB phototherapy: a first retrospective study. Acta Derm Venereol. 2004; 84 370-374
- 21 Hannuksela-Svahn A, Sigurgeirsson B, Pukkala E et al. Trioxsalen bath PUVA did not increase the risk of squamous cell skin carcinoma and cutaneous malignant melanoma in a joint analysis of 944 Swedish and Finnish patients with psoriasis. Br J Dermatol. 1999; 141 497-501
Dr. med. Markus Krug
Universitäts-Hautklinik
Eberhard-Karls-Universität
Liebermeisterstr. 25
72076 Tübingen
Email: markus.krug@med.uni-tuebingen.de