Effects on Wavefront Aberration after Short-term Wear of Senofilcon A Photochromic Contact Lens

 

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Abstract

Background To assess the variability in wavefront aberrations with short-term wear of photochromic senofilcon A contact lenses in both its activated and inactive states.

Methods and Material In this cross-sectional study, 20 participants who had previously used soft contact lenses were enrolled. Corneal aberrometry measurements were performed on each subject, without contact lenses, using Sirius Scheimpflug-Placido topography. The photochromic lenses were illuminated using a blue-violet light (λ _max = 420 nm) so as to provoke an activated state, and measurements were taken with the lenses inserted, in both states. The root mean square (RMS) of the aberrations was calculated, and the higher- and lower-order aberrations, astigmatism, coma, spherical aberration, and trefoil measurements were evaluated using a 5.0-mm pupil diameter.

Results The average contact lens sphere power was − 2.33 ± 1.07 D. The mean refractive errors with contact lens wear were 0.07 ± 0.18 D for the sphere and − 0.26 ± 0.15 D for the cylinder. The mean RMS values for all the corneal aberrations showed no statistically significant differences with and without contact lenses (p > 0.05). In a bivariate correlation analysis, there was a positive correlation between contact lens sphere power and coma (vertical and horizontal) in the activated state (r = 0.455, p = 0.44 and r = 0.495, p = 0.27, respectively).

Conclusion The photochromic contact lenses did not influence ocular aberration during short-term wear, even when the photochromatic additive was activated. This property may help to provide more comfortable vision with lens wear. This finding needs to be verified by further studies.

Zusammenfassung

Hintergrund Untersuchung der Variabilität der Wellenfrontaberrationen beim kurzfristigen Tragen von photochromen Senofilcon-Kontaktlinsen im aktivierten wie auch im inaktiven Zustand.

Methoden 20 Teilnehmer, die zuvor weiche Kontaktlinsen getragen hatten, nahmen an dieser Querschnittsstudie teil. Die aberrometrischen Messungen der Hornhaut wurden bei jedem Probanden ohne Kontaktlinsen mit der Sirius Scheimpflug-Placido-Topografie durchgeführt. Die photochromen Linsen wurden mit blauviolettem Licht (λmax = 420 nm) beleuchtet, um einen aktivierten Zustand zu erzeugen, und die Messungen wurden mit den Linsen in beiden Zuständen durchgeführt. Der RMS (root mean square) der Aberrationen wurde berechnet und die Aberrationen höherer und niedrigerer Ordnung, Astigmatismus, Koma, sphärische Aberration und Trefoil-Messungen wurden mit einem Pupillendurchmesser von 5,0 mm ausgewertet.

Ergebnisse Die durchschnittliche Stärke der Kontaktlinsen betrug − 2,33 ± 1,07 dpt. Die durchschnittlichen Brechungsfehler beim Tragen von Kontaktlinsen betrugen 0,07 ± 0,18 dpt für die Sphäre und − 0,26 ± 0,15 dpt für den Zylinder. Die mittleren RMS-Werte für alle Hornhautdefekte zeigten keine statistisch signifikanten Unterschiede mit und ohne Kontaktlinsen (p > 0,05). Eine bivariate Korrelationsanalyse zeigte eine positive Korrelation zwischen Kontaktlinsenstärke und Koma (vertikal und horizontal) im aktivierten Zustand (r = 0,455; p = 0,44; enr = 0,495; p = 0,27, entsprechend).

Schlussfolgerung Die photochromen Kontaktlinsen hatten keinen Einfluss auf die okulare Aberration während des kurzzeitigen Tragens, selbst wenn der photochrome Zusatzstoff aktiviert war. Diese Eigenschaft kann zu einer komfortableren Sicht beim Tragen von Kontaktlinsen beitragen. Dieses Ergebnis muss durch weitere Studien überprüft werden.

Publication History

Received: 15 May 2022

Accepted: 04 November 2022

Accepted Manuscript online:
08 November 2022

Article published online:
23 December 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

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