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Synthesis 1991; 1991(4): 265-266
DOI: 10.1055/s-1991-26440
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A Convenient Synthesis of 1,2,4-Oxadiazolidine-3,5-dione

P. Renaut* , D. Thomas, F. D. Bellamy
  • *Laboratoires Fournier, Centre de Recherche, 50 rue de Dijon, Daix, F-21121 Fontaine les Dijon, France
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Publication Date:
29 April 2002 (online)

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A convenient three-step synthesis of 1,2,4-oxadiazolidine-3,5-dione involving debenzylation of 3-benzyloxy-1,2,4-oxadiazol-5(4H)-one with boron tribromide is reported. By contrast with the two known procedures, this synthesis requires only nonhazardous and commercially available reagents.

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