Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)
Regular ArticleProtective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus
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Bioactive lipids and gut microbiota interact to regulate health and disease
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2021, Archives of Medical ResearchResolvin D1 Ameliorates Nicotinamide-streptozotocin-induced Type 2 Diabetes Mellitus by its Anti-inflammatory Action and Modulating PI3K/Akt/mTOR Pathway in the Brain
2020, Archives of Medical ResearchCitation Excerpt :Anti-inflammatory therapies represent a potential approach for treatment of diabetes complications including neuropathy (1–3,40,41). Previously, we reported that PUFAs have cytoprotective action against alloxan and streptozotocin-induced cytotoxicity to pancreatic β cells and prevent the development of both type 1 and type 2 diabetes mellitus (20–27,37) and at least, in part, this action seems to be mediated by the anti-inflammatory metabolites of PUFAs. In a previous study, we showed that alloxan-induced type 1 diabetic animals that received supplementation of PUFAs have almost normal pancreatic β cell mass (21–24).
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2020, Archives of Medical ResearchPredictive metabolic signatures for the occurrence and development of diabetic nephropathy and the intervention of Ginkgo biloba leaves extract based on gas or liquid chromatography with mass spectrometry
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