Regular ArticleSuppression of lymphoproliferation by alveolar macrophages in the guinea pig
References (33)
- et al.
Human alveolar macrophages suppress the proliferative response of peripheral blood lymphocytes
Chest
(1982) Alveolar macrophages. IV. Interspecies differences in activity in proliferating lymphocyte cultures
Cell Immuno
(1980)- et al.
The alveolar macrophage: its capacity as an accessory cell in mitogen-stimulated proliferation of guinea pig lymphocytes
Cell Immunol
(1978) - et al.
Nitric oxide; a cytotoxic activated macrophage effector molecule
Biochem Biophys Res Commun
(1988) - et al.
Spectrum of immunoregulatory functions and properties of human alveolar macrophages
Am Rev Respir Dis
(1987) - et al.
Human alveolar macrophages support of lymphocyte response to mitogens and antigens: analysis and comparisons with autologous peripheral blood-derived monocytes and macrophages
Am Rev Respir Dis
(1983) - et al.
Modulation of mitogen-induced proliferation of autologous peripheral blood lymphocytes by human alveolar macrophages
Infect Immun
(1982) - et al.
The accessory cell function of human alveolar macrophages in specific T cell proliferation
J Immunol
(1984) Alveolar macrophages. II. Inhibition of lymphocyte proliferation by purified macrophages from rat lung
Immunology
(1979)Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages
Clin Exp Immunol
(1986)
Inhibitory activity of unstimulated alveolar macrophages on T-lymphocyte blastogenic response
Am Rev Respir Dis
Alveolar macrophages. III. Studies on the mechanism of inhibition of T cell proliferation
Immuno
Production of lymphocyte chemokinetic activity by stimulated alveolar macrophages
Exp Lung Res
Macrophage activation of allogeneic lymphocyte proliferation in the guinea pig mixed leukocyte culture
J Immunol
Antigen presentation by guinea pig alveolar macrophages
J Immunol
Macrophage-mediated suppression. I. Evidence for participation of both hydrogen peroxide and prostaglandins in suppression of murine lymphocyte proliferation
J Immunol
Cited by (22)
Evolution of foamy macrophages in the pulmonary granulomas of experimental tuberculosis models
2009, TuberculosisCitation Excerpt :FM produce NO,4 do have reduced antigen processing function31 and transiently suppress effector T cells.32 In fact, T cell suppression by FM has been demonstrated in vivo33 in infected mice; and alveolar macrophages from humans and most mammal species inhibit T cell proliferation in vitro.34 In this regard, the suppression function must not be necessarily linked to the production of NO, as it is demonstrated in guinea-pigs where the function of suppression of T cells by lung macrophages is due to cell-to-cell contact.33,35
Guinea pig model of Mycobacterium tuberculosis latent/dormant infection
2008, Microbes and InfectionCitation Excerpt :One of the possible reasons for this failure is the lack of established protocols to induce partial immunosupression in this animal species. Drugs such as cortisone [19] and nitric oxide synthase inhibitors [24] which have been used in mice models of latent infection to trigger reactivation do not work well as immunosuppressive agents in guinea pigs [25–27]. Notwithstanding this limitation, the proposed model constitutes an important alternative for studies of tuberculosis caused by exogenous re-infection with M. tuberculosis of individuals with latent infection, which in contrast to reactivation of latent infection, is considered the most common cause of disease development in tuberculosis endemic countries [28,29].
The progress of therapeutic vaccination with regard to tuberculosis
2016, Frontiers in MicrobiologyImmune modulation effect of porcine placenta extracts in weaned the pig
2013, Journal of Animal ScienceCharacteristics of suppressor macrophages induced by mycobacterial and protozoal infections in relation to alternatively activated M2 macrophages
2012, Clinical and Developmental Immunology