Regular ArticleAn evaluation of the gamma interferon test for detecting bovine tuberculosis in cattle 8 to 28 days after tuberculin skin testing
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Predicting bovine tuberculosis status of dairy cows from mid-infrared spectral data of milk using deep learning
2020, Journal of Dairy ScienceAccuracy of PCR, mycobacterial culture and interferon-γ assays for detection of Mycobacterium bovis in blood and milk samples from Egyptian dairy cows using Bayesian modelling
2020, Preventive Veterinary MedicineCitation Excerpt :Several studies have discussed the effect of previously performed skin test (SCT) on the Sp of IFN-γ test (Schiller et al., 2010; Good et al., 2011; Bakker, 2014). The SCT test may lead to an apparent increase in IFN-γ production (Schiller et al., 2010), but it has been suggested to perform the IFN-γ after 33 days to minimize the SCT effect on IFN-γ results (Ryan et al., 2000). In the present study, the influence of SCT was not anticipated as the SCT test was performed ∼45 days prior to the IFN-γ test.
Antigen-specific interferon-gamma release is decreased following the single intradermal comparative cervical skin test in African buffaloes (Syncerus caffer)
2018, Veterinary Immunology and ImmunopathologyThe effectiveness of parallel gamma-interferon testing in New Zealand's bovine tuberculosis eradication programme
2016, Preventive Veterinary MedicineCitation Excerpt :The sensitivity of the γ-IFN assay has been estimated to be between 73 and 100%, with a median sensitivity of 87.6% (de la Rua-Domenech et al., 2006). Under New Zealand conditions, the sensitivity was estimated to be 85% with a specificity of 93% for animals that had reacted positively in the CFT (Ryan et al., 2000), with the sensitivity considered equivalent or greater to that of the CFT. The sensitivity and specificity of the γ-IFN test is dependent on the cut-off value used for positive interpretation (Goodchild and Clifton-Hadley, 2001; Wood and Jones, 2001; de la Rua-Domenech et al., 2006).
Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats
2015, Research in Veterinary ScienceCitation Excerpt :The effect of a recent intradermal test on the results of the IFN-γ assay has been widely studied. Even though a variety of results have been reported, some authors suggested the risk of false positive reactions due to the recent PPD injection or its potential usefulness to increase Se in infected herds (Coad et al., 2010; Palmer et al., 2006; Ryan et al., 2000; Schiller et al., 2010). In the present study, the intradermal test was performed at weeks 11 and 22.
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