Clinical Challenges and Images in GIAn Aged Man With Massive Hepatosplenomegaly
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Answer to the Clinical Challenges and Images in GI Question: Image 3 (page 1467): Hairy Cell Leukemia
The differential diagnosis of massive hepatosplenomegaly should include chronic lymphocytic leukemia, hairy cell leukemia (HCL), prolymphocytic leukemia, and lymphoma in an aged man with lymphocytosis, thrombocytopenia, anemia, and lymphadenopathy. Tuberculosis, visceral leishmaniasis, and Gaucher's disease were excluded owing to inconsistent symptoms, examinations, and epidemiology.1 Periportal halo sign of CT may provide another clue because it has been reported in cases with secondary or
References (3)
- et al.
Enlargement of lymph nodes and spleen
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Cited by (1)
Hairy cell leukemia and variant in Taiwan: Report of a variant case and literature review
2011, International Journal of Clinical and Experimental Pathology
Conflicts of interest The authors disclose no conflicts.
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Copyright © 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.