CorrespondenceOn the complexity of human CD3− intraepithelial lymphocytes
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Origin and immunophenotype of aberrant IEL in RCDII patients
2012, Molecular ImmunologyCitation Excerpt :This suggests that cladribine exerts a similar effect on aberrant and normal IELs, and therefore we feel that the comparison of the phenotype of both cell types provides useful information regarding their respective characteristics. Currently it remains unclear whether this aberrant population originates from dedifferentiating mature IELs, or that it regards a monoclonal expansion of a unique, physiological subpopulation (Leon and Roy, 2004; Tjon et al., 2010). In this study, a heterogeneous TCR gene rearrangement pattern in duodenal biopsies of a relatively large series of RCDII patients was observed, and confirmed in three RCDII cell lines.
Malignant complications of coeliac disease
2005, Best Practice and Research: Clinical GastroenterologyIntraepithelial lymphocytes subsets in different forms of celiac disease
2016, Autoimmunity HighlightsAge-related variation of intraepithelial lymphocytes subsets in normal human duodenal mucosa
2007, Digestive Diseases and Sciences
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