Gastroenterology

Gastroenterology

Volume 126, Issue 4, April 2004, Pages 1217-1218
Gastroenterology

Correspondence
On the complexity of human CD3 intraepithelial lymphocytes

https://doi.org/10.1053/j.gastro.2004.02.039Get rights and content

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    This suggests that cladribine exerts a similar effect on aberrant and normal IELs, and therefore we feel that the comparison of the phenotype of both cell types provides useful information regarding their respective characteristics. Currently it remains unclear whether this aberrant population originates from dedifferentiating mature IELs, or that it regards a monoclonal expansion of a unique, physiological subpopulation (Leon and Roy, 2004; Tjon et al., 2010). In this study, a heterogeneous TCR gene rearrangement pattern in duodenal biopsies of a relatively large series of RCDII patients was observed, and confirmed in three RCDII cell lines.

  • Malignant complications of coeliac disease

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