Cigarette smoking, high-density lipoprotein cholesterol subfractions, and lecithin: Cholesterol acyltransferase in young women☆
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Cited by (32)
Impact of Smoking Status on Lipoprotein Subfractions: Data from an Untreated Chinese Cohort
2017, Biomedical and Environmental SciencesCurrent smokers with hyperlipidemia lack elevated preβ1-high-density lipoprotein concentrations
2017, Journal of Clinical LipidologyCitation Excerpt :On the other hand, Freeman et al. reported that LCAT activity was significantly lower in smokers than in age-matched, sex-matched, and body mass index–matched nonsmokers.43 Other authors have also found that LCAT activity44 or LCAT mass45 is significantly reduced in smokers compared with nonsmokers. Even if smoking decreases LCAT activity, low LCAT activity increases preβ1-HDL concentration because of delayed conversion of preβ1-HDL to α-migrating HDL.23,24
Association between cigarette smoking and dyslipidemia
2013, Immuno-Analyse et Biologie SpecialiseeCitation Excerpt :Catecholamines mediate lipolysis, causing an increase in plasma concentrations of free fatty acids and very LDL triglycerides. However, the mechanisms by which cigarette smoke lowers c-HDL is unknown [11]. Smokers also differ from non-smokers in their dietary habits.
The influence of two variants in the adenosine triphosphate-binding cassette transporter 1 gene on plasma lipids and carotid atherosclerosis
2008, Metabolism: Clinical and ExperimentalCitation Excerpt :The exact mechanisms influencing the cardiovascular risk by cigarette smoke are not fully elucidated. Alterations in activities of enzymes of the RCT such as lecithin:cholesterol acyl transferase, cholesteryl ester transfer protein, and phospholipids transfer protein and decreased insulin sensitivity may be involved in the decrease of HDL-C in smokers [29-31]. Recent reports suggest a role for ABCA1 in the regulation of inflammatory responses of macrophages and macrophage recruitment into the arterial wall [32-35].
A simple and precise method for measuring HDL-cholesterol subfractions by a single precipitation followed by homogenous HDL-cholesterol assay
2008, Journal of Lipid ResearchCitation Excerpt :Table 2 shows HDL3-C and HDL2-C levels determined by the ultracentrifugation technique and the single precipitation method with direct HDL-C assay or TC assay. The HDL2-C level was approximately double the HDL3-C level, as has been reported in Japanese subjects (20, 21). The HDL3-C level determined by ultracentrifugation and precipitation HDL assay was almost identical, and the difference between the two methods was <1 mg/dl, whereas the difference was greater when HDL3-C was measured by the TC assay (7 mg/dl).
Early Midlife Cardiovascular Health Influences Future HDL Metrics in Women: The SWAN HDL Study
2022, Journal of the American Heart Association
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Supported by a grant from the Nakamura Gakuen University.