ORIGINAL ARTICLEConvergent effects of growth factors, hormones, and fibronectin are necessary for the enterocyte differentiation of a colon adenocarcinoma cell line (HT29-D4)
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Cited by (13)
Effects of Thyroid Hormone on the Adaptation in Short Bowel Syndrome<sup>1</sup>
2009, Journal of Surgical ResearchCitation Excerpt :There are studies on thyroid hormone indicating increased intestinal differentiation, brush border enzyme activity, and differentiation factor activities in adult rats and other adult species [32–35]. Thyroid hormone acts on proliferation by structural and functional maturation of the mammalian small intestine, mitochondrial pathways, and several protein gene activation mechanisms [36–39]. There are limited numbers of studies that have been performed in adult rats showing increased enterocyte differentiation, increased intestinal brush border enzyme gene expression, with similar thyroid replacement doses used in the present study [32, 33].
Butyrate Induces Intestinal Sodium Absorption via Sp3-Mediated Transcriptional Up-Regulation of Epithelial Sodium Channels
2007, GastroenterologyCitation Excerpt :Because enterocytes differentiate during crypt-to-villus migration and ENaC is only functionally active in the fully differentiated surface epithelium,35 we wondered whether ENaC induction by butyrate is solely the consequence of HT-29/B6 differentiation. Therefore, we tested other known inducers of differentiation in HT-29 cells,36–38 as, eg, glucose-free culture (for 1, 7, 14 days), insulin (5 μg/mL for 24 hours), or varying concentrations of FCS (0%, 5%, 10% for 24 hours). However, none of these conditions led to induction of β- and γ-ENaC mRNA (data not shown).
Extracellular matrix proteins and chemoradiotherapy: α5β1 integrin as a predictive marker in rectal cancer
2002, European Journal of Surgical OncologyThyroid hormones and cancer: A comprehensive review of preclinical and clinical studies
2019, Frontiers in EndocrinologyParadoxical roles of FAK in tumor cell migration and metastasis
2009, Cell Cycle