Abstract
The musk shrew, Suncus murinus, is one of the primitive mammals and has a pair of palatine tonsils. In the present study, we investigated the blood microvascular architecture of the tonsil in this animal by scanning electron microscopy of corrosion casts. The paranodular arterioles entered the lymph nodule to form a coarse capillary plexus within the nodule. Some of the arterioles reached the dome region to give rise to a fine meshwork of dome subepithelial capillaries. This dome subepithelial capillary network did not show any hairpin or switch-back patterns, as seen in human and rabbit tonsils. Both of the nodular and dome capillaries were drained into the postcapillary venules in the periphery of the nodular or the paranodular region. On the surface of these cast venules, oval-shaped indentations were seen corresponding to the luminal surface of the high endothelial venules. These venules were collected into the large vein at the bottom of the tonsil. The blood vascular architecture of the musk shrew tonsil is basically the same as those of other mucosa-associated lymphoid tissues in mammals.
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Bhalla DK, Murakami T, Owen RL (1981) Microcirculation of intestinal lymphoid follicles in rat Payer’s patches. Gastroen-terology 81, 481–91.
Bhalla DK, Owen RL (1983) Migration of B and T lymphocytes to M cells in Peyer’s patch follicle epithelium: An auto-radiographic and immunocytochemical study in mice. Cell Immunol 81, 105–17.
Gowans LL, Knight EJ (1964) The route of recirculation of lymphocytes in the rat. Proc R Soc Br 159, 257–82.
Hayashi S, Kikuta A, Ohtsuka A, Masuda Y (1991) Microvascu-lar architecture of rat nasal associated lymphoid tissue. Arch Histol Cytol 54, 279–87.
Kondo K (1985) [Suncus Murinus Biology of the Laboratory Shrew.] Scientific Societies Press, Tokyo. (In Japanese.)
Murakami T (1971) Application of the scanning electron microscope to the study of the fine distribution of the blood vessels. Arch Histol Jpn 32, 445–54.
Ohtani O, Kikuta A, Terasawa K et al. (1989) Microvascular organization of the human palatine tonsils. Arch Histol Cytol 52, 493–500.
Ohtsuka A, Owen RL, Murakami T (1992) Relationship of blood microvasculature to structure and function in lymphoid tissue. In: Scanning Electron Microscopy of Vascular Casts: Methods and Applications (Motta PM, Murakami T, Fujita H, eds). Kluwer Academic Publishers, Boston, 99–109.
Okada S, Ohtsuka A, Akagi H, Nishizaki K, Masuda Y (1995) Blood Microvascular Organization of the Nasal-Associated Lymphoid Tissue of the Guinea Pig: a Scanning Electron Microscopic Study of Corrosion Casts. Acta Med Okayama 49, 213–9.
Saito H, Hayakawa W, Nosaka Y, Ino H, Saito H (1985) [The Tonsil.] Nihon-Iji-Shinpo-Sha, Tokyo. (In Japanese).
Stamper HB, Woodruff JJ (1976) Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules. J Exp Med 144, 828–33.
Sunami-Kataoka Y, Akagi H, Nishizaki K, Taguchi T, Murakami T, Ohtsuka A (2001) Chondroitin sulfate proteoglycan at the basal lamina beneath high endothelial cells in human palatine tonsils: a light and electron microscopic study using the cationic colloidal iron method. Arch Histol Cytol 64, 535–43.
Terasawa K, Ohtani O, Kikuta A et al. (1988) [Microvascular organization of the rabbit tonsil: a scanning electron microscopic study of corrosion casts.] Jpn J Tonsil 27, 18–22. (In Japanese with English summary).
Tohya K, Kimura M (1996) Preference of lymphocyte-homing to high endothelial venules in palatine tonsils of musk shrew (Suncus murinus). Acta Otolaryngol 523, 25–7.
Tohya K, Kimura M, Kakudo K, Kawamata J (1992) Immuno-histochemical studies in the distribution of lymphocytes in the peripheral and mucosal lymphoid tissues of laboratory musk shrews (Suncus murinus). Dev Comp Immunol 16, 473–83.
Yamaguchi K, Schoefl GI (1983) Blood vessels of the Peyer’s patch in the mouse. II. In vivo observations. Anat Rec 206, 403–17.
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Doi, A., Okano, M., Akagi, H. et al. Blood vascular architecture of the palatine tonsil in the musk shrew (Suncus murinus): scanning electron microscopic study of corrosion casts. Anato Sci Int 78, 62–67 (2003). https://doi.org/10.1046/j.0022-7722.2003.00040.x
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DOI: https://doi.org/10.1046/j.0022-7722.2003.00040.x