Unsaturated 8-, 9- and 10-membered medium ring lactams 1 (n= 1,2,3) have been prepared in good yield by the Claisen rearrangement of the vinyl-substituted precursors 3 in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU).
P. A. Evans, A. B. Holmes, R. P. McGeary, A. Nadin, K. Russell, P. J. O'Hanlon and N. D. Pearson, J. Chem. Soc., Perkin Trans. 1, 1996, 123 DOI: 10.1039/P19960000123
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