Photochemical cyclisation of 3-N-(dialkylaminomethyl)imidazole-2,4-diones to 1,3,7-triazabicyclo[3.3.0]octanes
Abstract
Ultraviolet irradiation of N-3 Mannich bases derived from hydantoin or from 5,5-disubstituted hydantoins (imidazole-2,4-diones), provides an efficient route to 1,3,7-triazabicyclo[3.3.0]octane derivatives by photocyclisation to the C-4 carbonyl group.