A dynamic reversible phenylboronic acid sensor for real-time determination of protein–carbohydrate interactions on living cancer cells†
Shuang
Chao, 
a
Zhichao
Pei
*a
a
Zhichao
Pei
*a
Abstract
Real-time detection of glycosylation on label-free cancer cell surfaces is of significance for the diagnosis and treatment of cancer. In this work, we have successfully developed a novel dynamic reversible sensor based on pH-sensitive phenylboronic esters to determine in real-time the binding kinetics of protein–carbohydrate interactions on suspension cancer cell surfaces using a quartz crystal microbalance (QCM) technique.
- This article is part of the themed collection: Chemosensors and Molecular Logic
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