Diastereoselective hydrogenation of arenes and pyridines using supported ruthenium nanoparticles under mild conditions†
Florian
Bourriquen, 
a
Julien
Hervochon,
ab
Ruiyang
Qu,
a
Stephan
Bartling,
a
Nils
Rockstroh,
a
Kathrin
Junge,
*a
Cédric
Fischmeister
b
and
Matthias
Beller
*a
a
Julien
Hervochon,
ab
Ruiyang
Qu,
a
Stephan
Bartling,
a
Nils
Rockstroh,
a
Kathrin
Junge,
*a
Cédric
Fischmeister
b
and
Matthias
Beller
*a
Abstract
A convenient and practical diastereoselective cis-hydrogenation of multi-substituted pyridines and arenes is reported. Applying a novel heterogeneous ruthenium catalyst, the corresponding piperidines and cyclohexanes are obtained in high yields (typically >80%) with a good functional group tolerance under mild conditions. The robust ruthenium supported catalyst is smoothly prepared and can be reused multiple times without activity loss.
Please wait while we load your content...
