Issue 19, 2022
From the journal:

RSC Advances

Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe†

Noriko Nakamura, ORCID logo a   Nobuaki Tanakab  and  Seiichi Ohta ORCID logo *abcd  

* Corresponding authors

a Institute of Engineering Innovation, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan
E-mail: s-ohta@sogo.t.u-tokyo.ac.jp

b Department of Chemical System Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

c Department of Bioengineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

d Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 4-2-8 Honcho, Kawaguchi, Saitama 332-0012, Japan

Abstract

Conjugated polymer nanoparticles (Pdots) are expected to be novel bioimaging and sensing probes. However, the size tuning required to control biological interactions has not been well established. Herein, we achieved a size-tunable synthesis of Pdots ranging from 30 to 200 nm by controlling the hydrolysis rate of the stabilising agent and evaluated their cellular imaging properties.

Graphical abstract: Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe

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Article information

DOI
https://doi.org/10.1039/D1RA09101H
Article type
Paper
Submitted
16 Dec 2021
Accepted
08 Apr 2022
First published
14 Apr 2022
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2022,12, 11606-11611

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Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe

N. Nakamura, N. Tanaka and S. Ohta, RSC Adv., 2022, 12, 11606 DOI: 10.1039/D1RA09101H

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