Issue 14, 2022
From the journal:

RSC Advances

Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches

T. P. Adarsh Krishna, ORCID logo †*a   Baldev Edachery†a  and  Sunil Athalathila  

* Corresponding authors

a R & D Division, Sreedhareeyam Farmherbs India Pvt. Ltd, Ernakulam (Dist.), Kerala, India-686 662
E-mail: adarshkrishnatp@gmail.com

Abstract

Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea corylifolia. It has been reported to possess a broad range of biological and pharmacological properties and is considered as a leading biomolecule. It is highly desirable to devise an efficient approach to access bakuchiol and its chemical biology applications. In this review we provided structural features, isolation methods, various chemical routes and late-stage functionalization (LSF) approaches for bakuchiol and its derivatives. Moreover, this review encompasses the structure–activity relationships (SAR), value-added contributions and future perspectives of bakuchiol

Graphical abstract: Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches

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Article information

DOI
https://doi.org/10.1039/D1RA08771A
Article type
Review Article
Submitted
01 Dec 2021
Accepted
06 Mar 2022
First published
21 Mar 2022
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2022,12, 8815-8832

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Bakuchiol – a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches

T. P. Adarsh Krishna, B. Edachery and S. Athalathil, RSC Adv., 2022, 12, 8815 DOI: 10.1039/D1RA08771A

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