The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3

Alexander Wade; Rameshu Rallabandi; Steven Lucas; Catrina Oberg; Aruna Gorusupudi; Paul S. Bernstein; Jon D. Rainier

doi:10.1039/D1OB00491C

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The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3†

Alexander Wade,^a Rameshu Rallabandi,

^a Steven Lucas,^a Catrina Oberg,

^a Aruna Gorusupudi,

^b Paul S. Bernstein^b and Jon D. Rainier

*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, University of Utah, 315 South, 1400 East, Salt Lake City, UT 84112, USA
E-mail: rainier@chem.utah.edu

^b Department of Ophthalmology and Visual Sciences, 65 Mario Capecchi Drive, Moran Eye Center, University of Utah, Salt Lake City, UT 84132, USA

Abstract

This article describes the synthesis of VLC-PUFA 32:6 n-3, D₂-labeled 32:6 n-3, and the uptake of 32:6 n-3 into mouse retinal tissue.

This article is part of the themed collection: Total synthesis in OBC

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DOI: https://doi.org/10.1039/D1OB00491C
Article type: Paper
Submitted: 13 Mar 2021
Accepted: 24 May 2021
First published: 26 May 2021

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Org. Biomol. Chem., 2021,19, 5563-5566

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The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3

A. Wade, R. Rallabandi, S. Lucas, C. Oberg, A. Gorusupudi, P. S. Bernstein and J. D. Rainier, Org. Biomol. Chem., 2021, 19, 5563 DOI: 10.1039/D1OB00491C

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Organic & Biomolecular Chemistry

The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3†

Abstract

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The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3

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